Table 2. Logistic regression of... | American Society of Hematology

Table 2.

Logistic regression of predictors of PN symptom resolution

Variable	OR (95% CI)	P value∗
Multivariate model
Medical history of PN	0.65 (0.15-2.79)	.56
Major response	11.21 (2.06-61.15)	.0052
Medical history pertinent to PN	2.04 (0.34-12.35)	.44
Prior antineoplastic therapy	0.90 (0.12-6.68)	.92
Pertinent concomitant medication	0.65 (0.15-2.79)	.56
Major response	10.67 (2.20-51.81)	.0033
Baseline anti-MAG antibody value, 10^–4 TU	0.72 (0.52-1.00)	.0486
Binary baseline anti-MAG antibody, ≤999 TU	1.93 (0.45-8.28)	.38
Maximum IgM reduction	0.98 (0.93-1.03)	.34
Maximum IgM percent reduction	1.03 (1.00-1.06)	.05
IgM reduction at the latest measurement at or before PN symptom resolution†	1.01 (0.97-1.06)	.52
IgM reduction at the next measurement after PN symptom resolution†	1.01 (0.96-1.06)	.71
Minimum IgM	0.98 (0.91-1.05)	.52
Normalized minimum IgM less than or equal to ULN‡	5.05 (0.98-25.99)	.05
Normalized minimum IgM ≤1.5× ULN‡	2.65 (0.70-10.07)	.15
Normalized minimum IgM ≤2× ULN‡	1.50 (0.43-5.22)	.52

Variable	OR (95% CI)	P value∗
Multivariate model
Medical history of PN	0.65 (0.15-2.79)	.56
Major response	11.21 (2.06-61.15)	.0052
Medical history pertinent to PN	2.04 (0.34-12.35)	.44
Prior antineoplastic therapy	0.90 (0.12-6.68)	.92
Pertinent concomitant medication	0.65 (0.15-2.79)	.56
Major response	10.67 (2.20-51.81)	.0033
Baseline anti-MAG antibody value, 10^–4 TU	0.72 (0.52-1.00)	.0486
Binary baseline anti-MAG antibody, ≤999 TU	1.93 (0.45-8.28)	.38
Maximum IgM reduction	0.98 (0.93-1.03)	.34
Maximum IgM percent reduction	1.03 (1.00-1.06)	.05
IgM reduction at the latest measurement at or before PN symptom resolution†	1.01 (0.97-1.06)	.52
IgM reduction at the next measurement after PN symptom resolution†	1.01 (0.96-1.06)	.71
Minimum IgM	0.98 (0.91-1.05)	.52
Normalized minimum IgM less than or equal to ULN‡	5.05 (0.98-25.99)	.05
Normalized minimum IgM ≤1.5× ULN‡	2.65 (0.70-10.07)	.15
Normalized minimum IgM ≤2× ULN‡	1.50 (0.43-5.22)	.52

Values in bold represent statistically significant associations with PN symptom resolution at P value <.05.

Or the maximum IgM reduction if the patient did not have PN symptom resolution.

ULN for IgM was defined as 2.3 g/L.