Sensitivity and specificity of caregiver-reported academic, behavioral, and social development for detecting neurocognitive impairment
Neurocognitive impairment >1.5 SD below the normative mean . | ||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Score∗ . | Grade retention . | History of learning difficulties . | Academic grades . | Concerns for learning . | Concerns for school behavior . | Concerns for social development . | Difficulty getting along with peers . | |||||||
Sensitivity . | Specificity . | Sensitivity . | Specificity . | Sensitivity . | Specificity . | Sensitivity . | Specificity . | Sensitivity . | Specificity . | Sensitivity . | Specificity . | Sensitivity . | Specificity . | |
VCI† | 0.45 | 0.85 | 0.62 | 0.66 | 0.6 | 0.64 | 0.55 | 0.68 | 0.24 | 0.81 | 0.1 | 0.93 | 0.96 | 0.071 |
PRI† | 0.4 | 0.86 | 0.64 | 0.67 | 0.68 | 0.66 | 0.49 | 0.69 | 0.85 | 0.2 | 0.13 | 0.92 | 0.072 | 0.93 |
Coding‡ | 0.31 | 0.82 | 0.56 | 0.64 | 0.62 | 0.61 | 0.59 | 0.7 | 0.26 | 0.83 | 0.16 | 0.91 | 0.94 | 0.072 |
Digit span‡ | 0.45 | 0.82 | 0.69 | 0.63 | 0.83 | 0.62 | 0.64 | 0.67 | 0.26 | 0.82 | 0.17 | 0.9 | 0.97 | 0.076 |
Letter word§ | 0.5 | 0.84 | 0.77 | 0.67 | 0.74 | 0.64 | 0.75 | 0.71 | 0.22 | 0.84 | 0.11 | 0.9 | 0.075 | 0.93 |
Math fluency§ | 0.37 | 0.89 | 0.59 | 0.72 | 0.58 | 0.67 | 0.56 | 0.75 | 0.22 | 0.85 | 0.15 | 0.93 | 0.084 | 0.93 |
≥2 impairments|| | 0.42 | 0.90 | 0.64 | 0.77 | 0.62 | 0.73 | 0.53 | 0.75 | 0.21 | 0.84 | 0.95 | 0.07 | 0.97 | 0.08 |
Neurocognitive impairment >1 SD below the normative mean | ||||||||||||||
Score∗ | Grade retention | History of learning difficulties | Academic grades | Concerns for learning | Concerns for school behavior | Concerns for social development | Difficulty getting along with peers | |||||||
Sensitivity | Specificity | Sensitivity | Specificity | Sensitivity | Specificity | Sensitivity | Specificity | Sensitivity | Sensitivity | Specificity | Sensitivity | Specificity | Sensitivity | |
VCI† | 0.43 | 0.91 | 0.56 | 0.69 | 0.61 | 0.69 | 0.48 | 0.70 | 0.21 | 0.81 | 0.11 | 0.94 | 0.93 | 0.068 |
PRI† | 0.31 | 0.91 | 0.46 | 0.68 | 0.51 | 0.68 | 0.42 | 0.72 | 0.83 | 0.20 | 0.91 | 0.089 | 0.093 | 0.95 |
Coding‡ | 0.34 | 0.86 | 0.49 | 0.64 | 0.56 | 0.63 | 0.47 | 0.70 | 0.22 | 0.83 | 0.14 | 0.91 | 0.93 | 0.073 |
Digit span‡ | 0.39 | 0.84 | 0.59 | 0.65 | 0.71 | 0.64 | 0.58 | 0.70 | 0.21 | 0.82 | 0.17 | 0.91 | 0.94 | 0.075 |
Letter word§ | 0.42 | 0.88 | 0.69 | 0.73 | 0.75 | 0.71 | 0.61 | 0.74 | 0.22 | 0.85 | 0.14 | 0.91 | 0.10 | 0.94 |
Math fluency§ | 0.33 | 0.92 | 0.55 | 0.78 | 0.57 | 0.73 | 0.49 | 0.78 | 0.20 | 0.85 | 0.13 | 0.93 | 0.082 | 0.93 |
≥2 impairments|| | 0.32 | 0.96 | 0.47 | 0.79 | 0.52 | 0.82 | 0.41 | 0.77 | 0.84 | 0.18 | 0.07 | 0.94 | 0.07 | 0.93 |
Neurocognitive impairment >1.5 SD below the normative mean . | ||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Score∗ . | Grade retention . | History of learning difficulties . | Academic grades . | Concerns for learning . | Concerns for school behavior . | Concerns for social development . | Difficulty getting along with peers . | |||||||
Sensitivity . | Specificity . | Sensitivity . | Specificity . | Sensitivity . | Specificity . | Sensitivity . | Specificity . | Sensitivity . | Specificity . | Sensitivity . | Specificity . | Sensitivity . | Specificity . | |
VCI† | 0.45 | 0.85 | 0.62 | 0.66 | 0.6 | 0.64 | 0.55 | 0.68 | 0.24 | 0.81 | 0.1 | 0.93 | 0.96 | 0.071 |
PRI† | 0.4 | 0.86 | 0.64 | 0.67 | 0.68 | 0.66 | 0.49 | 0.69 | 0.85 | 0.2 | 0.13 | 0.92 | 0.072 | 0.93 |
Coding‡ | 0.31 | 0.82 | 0.56 | 0.64 | 0.62 | 0.61 | 0.59 | 0.7 | 0.26 | 0.83 | 0.16 | 0.91 | 0.94 | 0.072 |
Digit span‡ | 0.45 | 0.82 | 0.69 | 0.63 | 0.83 | 0.62 | 0.64 | 0.67 | 0.26 | 0.82 | 0.17 | 0.9 | 0.97 | 0.076 |
Letter word§ | 0.5 | 0.84 | 0.77 | 0.67 | 0.74 | 0.64 | 0.75 | 0.71 | 0.22 | 0.84 | 0.11 | 0.9 | 0.075 | 0.93 |
Math fluency§ | 0.37 | 0.89 | 0.59 | 0.72 | 0.58 | 0.67 | 0.56 | 0.75 | 0.22 | 0.85 | 0.15 | 0.93 | 0.084 | 0.93 |
≥2 impairments|| | 0.42 | 0.90 | 0.64 | 0.77 | 0.62 | 0.73 | 0.53 | 0.75 | 0.21 | 0.84 | 0.95 | 0.07 | 0.97 | 0.08 |
Neurocognitive impairment >1 SD below the normative mean | ||||||||||||||
Score∗ | Grade retention | History of learning difficulties | Academic grades | Concerns for learning | Concerns for school behavior | Concerns for social development | Difficulty getting along with peers | |||||||
Sensitivity | Specificity | Sensitivity | Specificity | Sensitivity | Specificity | Sensitivity | Specificity | Sensitivity | Sensitivity | Specificity | Sensitivity | Specificity | Sensitivity | |
VCI† | 0.43 | 0.91 | 0.56 | 0.69 | 0.61 | 0.69 | 0.48 | 0.70 | 0.21 | 0.81 | 0.11 | 0.94 | 0.93 | 0.068 |
PRI† | 0.31 | 0.91 | 0.46 | 0.68 | 0.51 | 0.68 | 0.42 | 0.72 | 0.83 | 0.20 | 0.91 | 0.089 | 0.093 | 0.95 |
Coding‡ | 0.34 | 0.86 | 0.49 | 0.64 | 0.56 | 0.63 | 0.47 | 0.70 | 0.22 | 0.83 | 0.14 | 0.91 | 0.93 | 0.073 |
Digit span‡ | 0.39 | 0.84 | 0.59 | 0.65 | 0.71 | 0.64 | 0.58 | 0.70 | 0.21 | 0.82 | 0.17 | 0.91 | 0.94 | 0.075 |
Letter word§ | 0.42 | 0.88 | 0.69 | 0.73 | 0.75 | 0.71 | 0.61 | 0.74 | 0.22 | 0.85 | 0.14 | 0.91 | 0.10 | 0.94 |
Math fluency§ | 0.33 | 0.92 | 0.55 | 0.78 | 0.57 | 0.73 | 0.49 | 0.78 | 0.20 | 0.85 | 0.13 | 0.93 | 0.082 | 0.93 |
≥2 impairments|| | 0.32 | 0.96 | 0.47 | 0.79 | 0.52 | 0.82 | 0.41 | 0.77 | 0.84 | 0.18 | 0.07 | 0.94 | 0.07 | 0.93 |
Scaled scores with mean (SD) of 10 (3): Coding, Digit Span Total; standard scores with a mean (SD) of 100 (15): VCI, PRI, Letter Word, Math Fluency.
Measured with WASI-II.
Measured with WAIS-IV or WISC-IV/V.
Measured with WJ-III/IV.
Participants were classified as having significant or mild neurocognitive impairment if they performed >1.5 or >1 SD below the normative data on ≥2 out of 6 neurocognitive measures, respectively.