Hematologic parameters of β3(R760C) KI mice
| Parameter . | WT . | Hetero . | Homo . |
|---|---|---|---|
| WBC (×109/L) | 5.46 (2.40-8.60) | 6.58 (2.40-12.70) | 4.38 (2.90-6.00) |
| RBC (×1012/L) | 10.07 (9.56-10.46) | 9.85 (9.30-10.78) | 9.79 (8.46-10.93) |
| Hb (g/dL) | 14.5 (13.9-14.8) | 14.3 (13.4-15.4) | 14.0 (12.3-15.5) |
| PLT (×109/L) | 1095 (1043-1183) | 834 (689-949)∗ | 445 (360-496)∗ |
| RP% | 8.04 (7.68-8.24) | 8.39 (7.73-8.87) | 8.62 (8.30-8.78) |
| TPO (pg/mL) | 283 (233-330) | 208 (203-219) | 270 (233-345) |
| Parameter . | WT . | Hetero . | Homo . |
|---|---|---|---|
| WBC (×109/L) | 5.46 (2.40-8.60) | 6.58 (2.40-12.70) | 4.38 (2.90-6.00) |
| RBC (×1012/L) | 10.07 (9.56-10.46) | 9.85 (9.30-10.78) | 9.79 (8.46-10.93) |
| Hb (g/dL) | 14.5 (13.9-14.8) | 14.3 (13.4-15.4) | 14.0 (12.3-15.5) |
| PLT (×109/L) | 1095 (1043-1183) | 834 (689-949)∗ | 445 (360-496)∗ |
| RP% | 8.04 (7.68-8.24) | 8.39 (7.73-8.87) | 8.62 (8.30-8.78) |
| TPO (pg/mL) | 283 (233-330) | 208 (203-219) | 270 (233-345) |
Peripheral blood was obtained from 8- to 10-week-old male mice. The average (range) is shown (n = 6).
Hb, hemoglobin; Hct, hematocrit; MCV, mean corpuscular volume; PLT, platelet count; RBC, red blood cell count; RP%, percentage of reticulated platelets; WBC, white blood cell count.
P < .05 vs WT.