Multivariate linear regression analysis of platelet counts and biomarkers of inflammation and cardiovascular risk
| Biomarker . | Regression coefficient (95% CI)∗, P value† . | |||
|---|---|---|---|---|
| Total study participants (n = 119) . | PWH (n = 90) . | |||
| Coefficient (95% CI)∗ . | P value† . | Coefficient (95% CI)∗ . | P value† . | |
| D-dimer | 0.00 (0.00-0.00) | .12 | 0.00 (0.00-0.00) | . 24 |
| CRP | 0.02 (−0.01 to 0.04) | .15 | 0.02 (−0.02 to 0.04) | .42 |
| sE-selectin | 0.01 (−0.01 to 0.03) | .12 | −0.01 (−0.03 to 0.02) | .63 |
| sP-selectin | 0.04 (−0.03 to 0.07) | .44 | 0.00 (−0.06 to 0.08) | .96 |
| sVCAM1 | −1.60 (−2.5 to −0.66) | <.001‡ | −1.90 (−3.2 to −0.58) | .005‡ |
| FRS | −0.02 (−0.03 to 0.00) | .041 | −0.01 (−0.04 to 0.01) | .22 |
| Paracardial fat volume | −0.21 (−0.42 to −0.00) | .054 | −0.21 (−0.51 to 0.10) | .18 |
| Epicardial fat volume | −0.31 (−0.60 to −0.02) | .035 | −0.30 (−0.70 to 0.10) | .14 |
| Pericardial fat volume§ | −0.52 (−0.99 to −0.05) | .032 | −0.51 (−1.2 to 0.16) | .14 |
| Biomarker . | Regression coefficient (95% CI)∗, P value† . | |||
|---|---|---|---|---|
| Total study participants (n = 119) . | PWH (n = 90) . | |||
| Coefficient (95% CI)∗ . | P value† . | Coefficient (95% CI)∗ . | P value† . | |
| D-dimer | 0.00 (0.00-0.00) | .12 | 0.00 (0.00-0.00) | . 24 |
| CRP | 0.02 (−0.01 to 0.04) | .15 | 0.02 (−0.02 to 0.04) | .42 |
| sE-selectin | 0.01 (−0.01 to 0.03) | .12 | −0.01 (−0.03 to 0.02) | .63 |
| sP-selectin | 0.04 (−0.03 to 0.07) | .44 | 0.00 (−0.06 to 0.08) | .96 |
| sVCAM1 | −1.60 (−2.5 to −0.66) | <.001‡ | −1.90 (−3.2 to −0.58) | .005‡ |
| FRS | −0.02 (−0.03 to 0.00) | .041 | −0.01 (−0.04 to 0.01) | .22 |
| Paracardial fat volume | −0.21 (−0.42 to −0.00) | .054 | −0.21 (−0.51 to 0.10) | .18 |
| Epicardial fat volume | −0.31 (−0.60 to −0.02) | .035 | −0.30 (−0.70 to 0.10) | .14 |
| Pericardial fat volume§ | −0.52 (−0.99 to −0.05) | .032 | −0.51 (−1.2 to 0.16) | .14 |
CRP, C-reactive protein.
Multivariable linear regression analysis adjusting for smoking status (ever vs never), diabetes, and HIV status.
Raw P value was reported.
If raw P <.005, statistical significance holds under Bonferroni-corrected type I error.
Pericardial fat volume is a composite of paracardial and epicardial fat volume.