Table 1.

Demographic profiles and azathioprine characteristics for all 92 patients with ITP who received azathioprine

Demographic profilesn (%)
Sex  
 Male 39 (42.4%) 
 Female 53 (57.6%) 
Age at diagnosis, mean (± SD), y 55.6 (± 22.3) 
Diagnosis  
 Primary ITP 64 (69.6%) 
 Secondary ITP  28 (30.4%) 
Baseline platelet count, median (range), × 109/L 22 (4-217) 
Duration of ITP before starting azathioprine, median (range), wk 71 (1-2499) 
Duration of follow-up, median (range), wk 338 (7-2801) 
Azathioprine characteristics  
 Starting dose, median (range), mg/d 100 (25-150) 
 Maintenance dose, median (range), mg/d 100 (25-150) 
 Duration of treatment, median (range), wk 20 (1-1787) 
Concurrent therapies  
 Corticosteroids 38 (41.3%) 
 Other immunosuppressive drugs 11 (12.0%) 
 TPO-RA 7 (7.6%) 
Demographic profilesn (%)
Sex  
 Male 39 (42.4%) 
 Female 53 (57.6%) 
Age at diagnosis, mean (± SD), y 55.6 (± 22.3) 
Diagnosis  
 Primary ITP 64 (69.6%) 
 Secondary ITP  28 (30.4%) 
Baseline platelet count, median (range), × 109/L 22 (4-217) 
Duration of ITP before starting azathioprine, median (range), wk 71 (1-2499) 
Duration of follow-up, median (range), wk 338 (7-2801) 
Azathioprine characteristics  
 Starting dose, median (range), mg/d 100 (25-150) 
 Maintenance dose, median (range), mg/d 100 (25-150) 
 Duration of treatment, median (range), wk 20 (1-1787) 
Concurrent therapies  
 Corticosteroids 38 (41.3%) 
 Other immunosuppressive drugs 11 (12.0%) 
 TPO-RA 7 (7.6%) 

SD, standard deviation.

Defined as all forms of ITP except primary ITP; most patients had concomitant autoimmune diseases.

Defined as the dose at which patients were maintained on the longest to maintain the desired therapeutic effect.

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