Table 2.

Data for BsAb in treating R/R MCL

Agent’NActivity
Epcoritamab18  One patient with CR, 1 PR, and 1 stable disease. Both responses occurred in patients with blastoid or pleomorphic MCL. 
Glofitamab21,22  29 ORR 85%, CR 78.3%; mDOR 16.2 mo, mDOCR 15.4 mo 
Mosunetuzumab + polatuzumab-vedotin23,24  20 ORR 75%, CRR 70%; mDOCR NR 
Odronextamab25  12 ORR 50%, CRR 33%; mDOR 10.9 mo 
Agent’NActivity
Epcoritamab18  One patient with CR, 1 PR, and 1 stable disease. Both responses occurred in patients with blastoid or pleomorphic MCL. 
Glofitamab21,22  29 ORR 85%, CR 78.3%; mDOR 16.2 mo, mDOCR 15.4 mo 
Mosunetuzumab + polatuzumab-vedotin23,24  20 ORR 75%, CRR 70%; mDOCR NR 
Odronextamab25  12 ORR 50%, CRR 33%; mDOR 10.9 mo 

CRR, complete response rate; NR, not reached.

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