Table 1.

Factors determining treatment selection

Main categorySpecific factors
Clinical factors Presence of bleeding, risk of bleeding, thromboembolism, and infection 
Access to medications Availability of medication/expertise, regulatory restrictions, label, and price 
Patient profile Age, concurrent medications (eg, anticoagulants), comorbidities, desire for pregnancy in women of childbearing age 
Drug properties Onset of action, efficacy, safety profiles, effect on HRQoL, and induction of SROT 
Patient preferences Maintenance or remission-inducing therapies, compliance, lifestyle, and hobbies 
Main categorySpecific factors
Clinical factors Presence of bleeding, risk of bleeding, thromboembolism, and infection 
Access to medications Availability of medication/expertise, regulatory restrictions, label, and price 
Patient profile Age, concurrent medications (eg, anticoagulants), comorbidities, desire for pregnancy in women of childbearing age 
Drug properties Onset of action, efficacy, safety profiles, effect on HRQoL, and induction of SROT 
Patient preferences Maintenance or remission-inducing therapies, compliance, lifestyle, and hobbies 

HRQoL, health-related quality of life; SROT, sustained response off-treatment.

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