Enrollment in the pediatric stratum of the BMT CTN 1507 trial of HLA-haploidentical HCT for SCD
| Stage . | Enrollment per stage and symptom . | Total . |
|---|---|---|
| 4 | Stoke only (n = 12) Stroke and aTCD (n = 3) Stroke and SCI (n = 1) Stroke and SCI and aTCD (n = 1) | 17 |
| 3 | SCI only (n = 7) aTCD only (n = 3) SCI and aTCD (n = 1) aTCD and ACS and severe vaso-occlusive pain per adjudication (n = 1) | 12 |
| 2 | ACS (n = 3) Right heart catheter defined pHTN (n = 0) Essential HTN despite therapy (n = 0) Severe vaso-occlusive pain by adjudication (n = 5) Priapism per adjudication (n = 0) ACS and severe vaso-occlusive pain by adjudication (n = 4) | 12 |
| 1 | Not open for enrollment |
| Stage . | Enrollment per stage and symptom . | Total . |
|---|---|---|
| 4 | Stoke only (n = 12) Stroke and aTCD (n = 3) Stroke and SCI (n = 1) Stroke and SCI and aTCD (n = 1) | 17 |
| 3 | SCI only (n = 7) aTCD only (n = 3) SCI and aTCD (n = 1) aTCD and ACS and severe vaso-occlusive pain per adjudication (n = 1) | 12 |
| 2 | ACS (n = 3) Right heart catheter defined pHTN (n = 0) Essential HTN despite therapy (n = 0) Severe vaso-occlusive pain by adjudication (n = 5) Priapism per adjudication (n = 0) ACS and severe vaso-occlusive pain by adjudication (n = 4) | 12 |
| 1 | Not open for enrollment |
Eligibility was stepwise after National Heart, Lung, and Blood Institute-appointmentd protocol review committee and DSMB panel insight.