Recommended monitoring frequency of ALT after valoctocogene roxaparvovec gene therapy for HA
| Time frame . | Monitoring frequency . |
|---|---|
| ALT levels | |
| First 26 wk | Weekly |
| Week 26 to 52 (year 1) | Every 1-2 wk |
| Year 2 | Every 3 mo |
| After year 2 | Every 6 mo |
| Imaging | |
| Ultrasound | At least once a year |
| TE | At least once a year |
| Time frame . | Monitoring frequency . |
|---|---|
| ALT levels | |
| First 26 wk | Weekly |
| Week 26 to 52 (year 1) | Every 1-2 wk |
| Year 2 | Every 3 mo |
| After year 2 | Every 6 mo |
| Imaging | |
| Ultrasound | At least once a year |
| TE | At least once a year |