Binding of INCA033989 to wt and mutCALR proteins
| Analyte . | Antibody . | ka (M−1s–1) . | kd (s–1) . | KD (nM) . |
|---|---|---|---|---|
| MBP-mutCALRdel52 | INCA033989 | 1.14 × 106 | 1.99 × 10–3 | 1.75 |
| MBP-mutCALRins5 | INCA033989 | 8.54 × 105 | 5.79 × 10–3 | 6.78 |
| Analyte . | Antibody . | ka (M−1s–1) . | kd (s–1) . | KD (nM) . |
|---|---|---|---|---|
| MBP-mutCALRdel52 | INCA033989 | 1.14 × 106 | 1.99 × 10–3 | 1.75 |
| MBP-mutCALRins5 | INCA033989 | 8.54 × 105 | 5.79 × 10–3 | 6.78 |
ka, association rate constant; kd, dissociation rate constant; KD, dissociation constant; MBP, maltose-binding protein.