Hematologic parameters of experimental mice
Genotype . | RBCs (106/μL) . | Hct (%) . | MCV (fL) . | Mean cell Hb (pg) . | Mean cell Hb concentration (g/dL) . | Hb distribution width (g/dL) . | Red cell distribution width (%) . |
---|---|---|---|---|---|---|---|
+/+ Dmt1+/+ | 10 ± 0.4a | 55 ± 2a | 54 ± 0.7a | 16 ± 1a | 29 ± 12a | 2 ± 0.1a | 15 ± 1a |
Th3/+ Dmt1+/+ | 7 ± 0.4b | 31 ± 1b | 42 ± 2b | 10 ± 1b | 23 ± 0.6b | 5 ± 0.2b | 38 ± 1b |
Th3/+ Dmt1int/+ | 7 ± 1b | 32 ± 3b | 44 ± 3b | 10 ± 1b | 23 ± 1b | 4 ± 0.5b | 37 ± 1b |
Th3/+ Dmt1int/int | 4 ± 1c | 13 ± 4c | 34 ± 1c | 7 ± 1c | 21 ± 1b | 5 ± 0.3b | 39 ± 4b |
P value∗ | <.01 | <.01 | <.01 | <.01 | <.01 | <.01 | <.01 |
Genotype . | RBCs (106/μL) . | Hct (%) . | MCV (fL) . | Mean cell Hb (pg) . | Mean cell Hb concentration (g/dL) . | Hb distribution width (g/dL) . | Red cell distribution width (%) . |
---|---|---|---|---|---|---|---|
+/+ Dmt1+/+ | 10 ± 0.4a | 55 ± 2a | 54 ± 0.7a | 16 ± 1a | 29 ± 12a | 2 ± 0.1a | 15 ± 1a |
Th3/+ Dmt1+/+ | 7 ± 0.4b | 31 ± 1b | 42 ± 2b | 10 ± 1b | 23 ± 0.6b | 5 ± 0.2b | 38 ± 1b |
Th3/+ Dmt1int/+ | 7 ± 1b | 32 ± 3b | 44 ± 3b | 10 ± 1b | 23 ± 1b | 4 ± 0.5b | 37 ± 1b |
Th3/+ Dmt1int/int | 4 ± 1c | 13 ± 4c | 34 ± 1c | 7 ± 1c | 21 ± 1b | 5 ± 0.3b | 39 ± 4b |
P value∗ | <.01 | <.01 | <.01 | <.01 | <.01 | <.01 | <.01 |
Hct, hematocrit; MCV, mean corpuscular volume; RBC, red blood cell.
Statistical analysis by 1-way analysis of variance. P values indicate significance of the genotype main effect for data in that column.