Table 1.

Hematologic parameters of experimental mice

GenotypeRBCs (106/μL)Hct (%)MCV (fL)Mean cell
Hb (pg)
Mean cell Hb concentration (g/dL)Hb distribution
width (g/dL)
Red cell distribution
width (%)
+/+
Dmt1+/+ 
10 ± 0.4a 55 ± 2a 54 ± 0.7a 16 ± 1a 29 ± 12a 2 ± 0.1a 15 ± 1a 
Th3/+
Dmt1+/+ 
7 ± 0.4b 31 ± 1b 42 ± 2b 10 ± 1b 23 ± 0.6b 5 ± 0.2b 38 ± 1b 
Th3/+
Dmt1int/+ 
7 ± 1b 32 ± 3b 44 ± 3b 10 ± 1b 23 ± 1b 4 ± 0.5b 37 ± 1b 
Th3/+
Dmt1int/int 
4 ± 1c 13 ± 4c 34 ± 1c 7 ± 1c 21 ± 1b 5 ± 0.3b 39 ± 4b 
P value  <.01 <.01 <.01 <.01 <.01 <.01 <.01 
GenotypeRBCs (106/μL)Hct (%)MCV (fL)Mean cell
Hb (pg)
Mean cell Hb concentration (g/dL)Hb distribution
width (g/dL)
Red cell distribution
width (%)
+/+
Dmt1+/+ 
10 ± 0.4a 55 ± 2a 54 ± 0.7a 16 ± 1a 29 ± 12a 2 ± 0.1a 15 ± 1a 
Th3/+
Dmt1+/+ 
7 ± 0.4b 31 ± 1b 42 ± 2b 10 ± 1b 23 ± 0.6b 5 ± 0.2b 38 ± 1b 
Th3/+
Dmt1int/+ 
7 ± 1b 32 ± 3b 44 ± 3b 10 ± 1b 23 ± 1b 4 ± 0.5b 37 ± 1b 
Th3/+
Dmt1int/int 
4 ± 1c 13 ± 4c 34 ± 1c 7 ± 1c 21 ± 1b 5 ± 0.3b 39 ± 4b 
P value  <.01 <.01 <.01 <.01 <.01 <.01 <.01 

Hct, hematocrit; MCV, mean corpuscular volume; RBC, red blood cell.

Statistical analysis by 1-way analysis of variance. P values indicate significance of the genotype main effect for data in that column.

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