Univariate and multivariate logistic regression analysis for MACE
| Parameter . | Univariate . | Multivariate . | ||
|---|---|---|---|---|
| OR (95 % CI) . | P value . | HR (95 % CI) . | P value . | |
| H3Cit-DNA >219.3 μg/L | 4.660 (2.649-8.196) | <.001 | 2.905 (1.099-7.679) | .032 |
| Sex (male) | 0.860 (0.563-1.314) | .486 | ||
| Age, y | 1.049 (1.032-1.067) | <.001 | 1.067 (1.016-1.121) | .01 |
| BMI, kg/m2 | 0.999 (0.956-1.044) | .971 | ||
| Diabetes mellitus | 1.384 (0.947-2.023) | .094 | 1.316 (0.509-3.404) | .571 |
| Current smoker | 0.598 (0.403-0.886) | .010 | 1.226 (0.419-3.587) | .71 |
| Total cholesterol, mg/dL | 0.986 (0.979-0.994) | .001 | 0.977 (0.948-1.008) | .14 |
| HDL cholesterol, mg/dL | 0.982 (0.959-1.005) | .127 | ||
| LDL cholesterol, mg/dL | 0.987 (0.978-0.996) | .006 | 1.033 (0.996-1.07) | .079 |
| GFR, mL/min | 0.969 (0.961-0.977) | <.001 | 1.002 (0.979-1.026) | .871 |
| CRP, mg/L | 1.201 (1.141-1.265) | <.001 | 1.147 (1.054-1.249) | .002 |
| TnT, mg/L | 1.000 (1.000-1.000) | <.001 | 1.000 (0.999-1.001) | .489 |
| Parameter . | Univariate . | Multivariate . | ||
|---|---|---|---|---|
| OR (95 % CI) . | P value . | HR (95 % CI) . | P value . | |
| H3Cit-DNA >219.3 μg/L | 4.660 (2.649-8.196) | <.001 | 2.905 (1.099-7.679) | .032 |
| Sex (male) | 0.860 (0.563-1.314) | .486 | ||
| Age, y | 1.049 (1.032-1.067) | <.001 | 1.067 (1.016-1.121) | .01 |
| BMI, kg/m2 | 0.999 (0.956-1.044) | .971 | ||
| Diabetes mellitus | 1.384 (0.947-2.023) | .094 | 1.316 (0.509-3.404) | .571 |
| Current smoker | 0.598 (0.403-0.886) | .010 | 1.226 (0.419-3.587) | .71 |
| Total cholesterol, mg/dL | 0.986 (0.979-0.994) | .001 | 0.977 (0.948-1.008) | .14 |
| HDL cholesterol, mg/dL | 0.982 (0.959-1.005) | .127 | ||
| LDL cholesterol, mg/dL | 0.987 (0.978-0.996) | .006 | 1.033 (0.996-1.07) | .079 |
| GFR, mL/min | 0.969 (0.961-0.977) | <.001 | 1.002 (0.979-1.026) | .871 |
| CRP, mg/L | 1.201 (1.141-1.265) | <.001 | 1.147 (1.054-1.249) | .002 |
| TnT, mg/L | 1.000 (1.000-1.000) | <.001 | 1.000 (0.999-1.001) | .489 |
BMI, body mass index; GFR, glomerular filtration rate calculated by Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation; HDL, high-density lipoprotein; HR, hazard ratio; LDL, low-density lipoprotein; OR, odds ratio; TnT, troponin T; 95% CI, 95% confidence interval. Boldface indicates P values were considered significant if P < 0.05.