Table 3. ITP case-control genome-wide... | American Society of Hematology

Table 3.

ITP case-control genome-wide association study summary results

SNV	Location	Gene symbol	Genomic location	MAF ITP	MAF controls	OR	SE	L95	U95	P value
rs4785426	16:50493430:A:G	Proximal to NKD1	Intergenic	0.13	0.28	0.48	0.09	0.40	0.57	1.84E−16
rs10967515	9:2684117:T:C	LOC105375957	Intergenic	0.07	0.18	0.40	0.11	0.32	0.51	2.99E−15
rs4785216	16:50579394:T:C	Proximal to NKD1	Intergenic	0.08	0.19	0.43	0.11	0.34	0.53	8.86E−15
rs2165798	11:19912781:G:A	NAV2	Intergenic	0.11	0.18	0.52	0.10	0.43	0.63	3.17E−11
rs8054390	16:86462937:A:G		Intergenic	0.02	0.02	3.98	0.24	2.48	6.41	1.25E−08
rs75650997	14:92867259:C:T	SLC24A4	Intergenic	0.04	0.02	2.38	0.16	1.75	3.24	3.89E−08

SNV	Location	Gene symbol	Genomic location	MAF ITP	MAF controls	OR	SE	L95	U95	P value
rs4785426	16:50493430:A:G	Proximal to NKD1	Intergenic	0.13	0.28	0.48	0.09	0.40	0.57	1.84E−16
rs10967515	9:2684117:T:C	LOC105375957	Intergenic	0.07	0.18	0.40	0.11	0.32	0.51	2.99E−15
rs4785216	16:50579394:T:C	Proximal to NKD1	Intergenic	0.08	0.19	0.43	0.11	0.34	0.53	8.86E−15
rs2165798	11:19912781:G:A	NAV2	Intergenic	0.11	0.18	0.52	0.10	0.43	0.63	3.17E−11
rs8054390	16:86462937:A:G		Intergenic	0.02	0.02	3.98	0.24	2.48	6.41	1.25E−08
rs75650997	14:92867259:C:T	SLC24A4	Intergenic	0.04	0.02	2.38	0.16	1.75	3.24	3.89E−08

Table describes variants which met genome-wide significance threshold is P < 5 × 10⁻⁸.

OR, odds ration; L95, lower bound of 95% confidence interval; SE, standard error; U95, upper bound of 95% confidence interval.