Mean minimum coagulation factor levels and frequencies of different coagulation factor level ranges in carriers and noncarriers
| . | HA carriers . | HA noncarriers . | Total . | P value . |
|---|---|---|---|---|
| FVIII minimum level | ||||
| Mean, IU/dL (SD) | 61.42 (28.20) | 117.93 (35.32) | <.001 | |
| <1 IU/dL, n (%) | 1 (0.5) | 0 (0.0) | 1 (0.4) | |
| 1-5 IU/dL, n (%) | 0 (0.0) | 0 (0.0) | 0 (0.0) | |
| 6-15 IU/dL, n (%) | 3 (1.6) | 0 (0.0) | 3 (1.3) | |
| 16-39 IU/dL, n (%) | 38 (20.8) | 0 (0.0) | 38 (15.8) | |
| 40-60 IU/dL, n (%) | 61 (33.3) | 1 (1.8) | 62 (25.8) | |
| ≥61 IU/dL, n (%) | 80 (43.7) | 56 (98.2) | 136 (56.7) | |
| Total, n | 183 | 57 | 240 | |
| VWF:Ag minimum level | ||||
| Mean, IU/dL (SD) | 111.19 (45.04) | 112.54 (38.10) | .853 | |
| VWF:RCo minimum level | ||||
| Mean, IU/dL (SD) | 107.80 (42.79) | 116.80 (44.56) | .221 |
| . | HA carriers . | HA noncarriers . | Total . | P value . |
|---|---|---|---|---|
| FVIII minimum level | ||||
| Mean, IU/dL (SD) | 61.42 (28.20) | 117.93 (35.32) | <.001 | |
| <1 IU/dL, n (%) | 1 (0.5) | 0 (0.0) | 1 (0.4) | |
| 1-5 IU/dL, n (%) | 0 (0.0) | 0 (0.0) | 0 (0.0) | |
| 6-15 IU/dL, n (%) | 3 (1.6) | 0 (0.0) | 3 (1.3) | |
| 16-39 IU/dL, n (%) | 38 (20.8) | 0 (0.0) | 38 (15.8) | |
| 40-60 IU/dL, n (%) | 61 (33.3) | 1 (1.8) | 62 (25.8) | |
| ≥61 IU/dL, n (%) | 80 (43.7) | 56 (98.2) | 136 (56.7) | |
| Total, n | 183 | 57 | 240 | |
| VWF:Ag minimum level | ||||
| Mean, IU/dL (SD) | 111.19 (45.04) | 112.54 (38.10) | .853 | |
| VWF:RCo minimum level | ||||
| Mean, IU/dL (SD) | 107.80 (42.79) | 116.80 (44.56) | .221 |
| . | HB carriers . | HB noncarriers . | Total . | P value . |
|---|---|---|---|---|
| FIX minimum level | ||||
| Mean, IU/dL (SD) | 59.36 (29.90) | 103.09 (30.40) | <.001 | |
| <1 IU/dL, n (%) | 1 (1.3) | 0 (0.0) | 1 (1.0) | |
| 1-5 IU/dL, n (%) | 0 (0.0) | 0 (0.0) | 0 (0.0) | |
| 6-15 IU/dL, n (%) | 1 (1.3) | 0 (0.0) | 1 (1.0) | |
| 16-39 IU/dL, n (%) | 21 (26.9) | 0 (0.0) | 21 (21.0) | |
| 40-60 IU/dL, n (%) | 19 (24.4) | 2 (9.1) | 21 (21.0) | |
| ≥61 IU/dL, n (%) | 36 (46.2) | 20 (90.9) | 56 (56.0) | |
| Total, n | 78 | 22 | 100 |
| . | HB carriers . | HB noncarriers . | Total . | P value . |
|---|---|---|---|---|
| FIX minimum level | ||||
| Mean, IU/dL (SD) | 59.36 (29.90) | 103.09 (30.40) | <.001 | |
| <1 IU/dL, n (%) | 1 (1.3) | 0 (0.0) | 1 (1.0) | |
| 1-5 IU/dL, n (%) | 0 (0.0) | 0 (0.0) | 0 (0.0) | |
| 6-15 IU/dL, n (%) | 1 (1.3) | 0 (0.0) | 1 (1.0) | |
| 16-39 IU/dL, n (%) | 21 (26.9) | 0 (0.0) | 21 (21.0) | |
| 40-60 IU/dL, n (%) | 19 (24.4) | 2 (9.1) | 21 (21.0) | |
| ≥61 IU/dL, n (%) | 36 (46.2) | 20 (90.9) | 56 (56.0) | |
| Total, n | 78 | 22 | 100 |
SD, standard deviation.