Table 3.

Efficacy of CAR19-22 with NKTR-255

CAR19-22 + NKTR-255 (n = 9)CAR19-22 control (n = 8)
CR/CRi 8 (89%) 7 (88%) 
MRD-negative 8 (89%) 6 (75%) 
Progression/relapse 3 (33%) 5 (62%) 
Consolidative HCT 2 (23%) 1 (13%) 
6-month RFS (%, 95% CI) 67% (42-100) 38% (15-92) 
12-month RFS (%, 95% CI) 67% (42-100) 38% (15-92) 
CAR19-22 + NKTR-255 (n = 9)CAR19-22 control (n = 8)
CR/CRi 8 (89%) 7 (88%) 
MRD-negative 8 (89%) 6 (75%) 
Progression/relapse 3 (33%) 5 (62%) 
Consolidative HCT 2 (23%) 1 (13%) 
6-month RFS (%, 95% CI) 67% (42-100) 38% (15-92) 
12-month RFS (%, 95% CI) 67% (42-100) 38% (15-92) 

CRi, complete response with incomplete count recovery; RFS, relapse free survival; MRD, measurable residual disease.

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