Clinical characteristics of 192 pediatric patients with T-LBL and 167 pediatric patients with T-ALL, differentiated by the presence of the TRB::NOTCH1
. | Patients with T-ALL . | Patients with T-LBL without TRB::NOTCH1 . | Patients with T-LBL with TRB::NOTCH1 . | P value . | |||
---|---|---|---|---|---|---|---|
n . | % . | n . | % . | n . | % . | ||
All | 167 | 180 | 12 | ||||
Sex | |||||||
Male | 126 | 75 | 128 | 71 | 9 | 75 | |
Female | 41 | 25 | 52 | 29 | 3 | 25 | >.99 |
Median age, y | 9.2 | 9.9 | 15.1 | ||||
<10 | 97 | 58 | 92 | 51 | 0 | 0 | |
10-14 | 50 | 30 | 66 | 37 | 5 | 42 | |
≥15 | 20 | 12 | 22 | 12 | 7 | 58 | .0004 |
Progression/relapse | 25 | 15 | 31 | 17 | 8 | 67 |
. | Patients with T-ALL . | Patients with T-LBL without TRB::NOTCH1 . | Patients with T-LBL with TRB::NOTCH1 . | P value . | |||
---|---|---|---|---|---|---|---|
n . | % . | n . | % . | n . | % . | ||
All | 167 | 180 | 12 | ||||
Sex | |||||||
Male | 126 | 75 | 128 | 71 | 9 | 75 | |
Female | 41 | 25 | 52 | 29 | 3 | 25 | >.99 |
Median age, y | 9.2 | 9.9 | 15.1 | ||||
<10 | 97 | 58 | 92 | 51 | 0 | 0 | |
10-14 | 50 | 30 | 66 | 37 | 5 | 42 | |
≥15 | 20 | 12 | 22 | 12 | 7 | 58 | .0004 |
Progression/relapse | 25 | 15 | 31 | 17 | 8 | 67 |