Occurrence of aGVHD in the different amino acid matching categories and in 10/10 MUDs, both for the main and validation cohort
| . | Grade 0-1 aGVHD . | Grade 2-4 aGVHD . | P value aGVHD . |
|---|---|---|---|
| TotalHvGmatching | .11 | ||
| mismatched (n = 57) | 44 (77%) | 13 (23%) | |
| matched (n = 13) | 13 (100%) | 0 (0%) | |
| TotalGvHmatching | .28 | ||
| mismatched (n = 53) | 45 (85%) | 8 (15%) | |
| matched (n = 17) | 12 (71%) | 5 (29%) | |
| αHvGmatching | .09 | ||
| mismatched (n = 49) | 37 (76%) | 12 (24%) | |
| matched (n = 21) | 20 (95%) | 1 (5%) | |
| αGvHmatching | .76 | ||
| mismatched (n = 38) | 30 (79%) | 8 (21%) | |
| matched (n = 32) | 27 (84%) | 5 (16%) | |
| βHvGmatching | .12 | ||
| mismatched (n = 39) | 29 (74%) | 10 (26%) | |
| matched (n = 31) | 28 (90%) | 3 (10%) | |
| βGvHmatching | 1 | ||
| mismatched (n = 35) | 28 (80%) | 7 (20%) | |
| matched (n = 35) | 29 (83%) | 6 (17%) | |
| 10/10 matched controls (n = 157) | 123 (78%) | 34 (22%) | |
| Validation cohort, MUD vs MMUD | .22 | ||
| 10/10 MUD (n = 894, 35 missing) | 621 (69%) | 273 (31%) | |
| 9/10 MMUD (n = 257, 14 missing) | 168 (65%) | 89 (35%) |
| . | Grade 0-1 aGVHD . | Grade 2-4 aGVHD . | P value aGVHD . |
|---|---|---|---|
| TotalHvGmatching | .11 | ||
| mismatched (n = 57) | 44 (77%) | 13 (23%) | |
| matched (n = 13) | 13 (100%) | 0 (0%) | |
| TotalGvHmatching | .28 | ||
| mismatched (n = 53) | 45 (85%) | 8 (15%) | |
| matched (n = 17) | 12 (71%) | 5 (29%) | |
| αHvGmatching | .09 | ||
| mismatched (n = 49) | 37 (76%) | 12 (24%) | |
| matched (n = 21) | 20 (95%) | 1 (5%) | |
| αGvHmatching | .76 | ||
| mismatched (n = 38) | 30 (79%) | 8 (21%) | |
| matched (n = 32) | 27 (84%) | 5 (16%) | |
| βHvGmatching | .12 | ||
| mismatched (n = 39) | 29 (74%) | 10 (26%) | |
| matched (n = 31) | 28 (90%) | 3 (10%) | |
| βGvHmatching | 1 | ||
| mismatched (n = 35) | 28 (80%) | 7 (20%) | |
| matched (n = 35) | 29 (83%) | 6 (17%) | |
| 10/10 matched controls (n = 157) | 123 (78%) | 34 (22%) | |
| Validation cohort, MUD vs MMUD | .22 | ||
| 10/10 MUD (n = 894, 35 missing) | 621 (69%) | 273 (31%) | |
| 9/10 MMUD (n = 257, 14 missing) | 168 (65%) | 89 (35%) |