Table 2.

Budget impact analysis, Medicaid perspective for United States and selected state programs

Total no. eligible for gene therapyNo. eligible for therapy per 100 000 plan enrolleesNo. to receive therapy, year 1Budget impact, year 1 (million USD)PMPM cost, year 1% change in year 1 PMPM cost from original model 6 PMPM cost, year 5
United States  7742 8.5 542 $1241.0 $1.13 18% $0.75 
Alabama 338 29.2 24 $54.2 $3.90 49% $2.60 
Washington, DC 69 23.6 $11.0 $3.15 45% $2.10 
Florida 904 18.7 63 $144.9 $2.50 41% $1.67 
Georgia 720 29.3 50 $115.4 $3.92 57% $2.61 
Louisiana 445 23.7 31 $71.4 $3.17 46% $2.11 
Maryland 329 19.7 23 $52.8 $2.63 59% $1.75 
Mississippi 203 26.5 14 $32.5 $3.55 –4% $2.36 
North Carolina 409 18.1 29 $65.5 $2.41 28% $1.60 
South Carolina 350 27.1 25 $56.1 $3.62 43% $2.42 
Virginia 339 17.2 24 $54.4 $2.30 20% $1.54 
Sample average 411 21.9 29 $65.8 $3.11 40% $2.08 
Total no. eligible for gene therapyNo. eligible for therapy per 100 000 plan enrolleesNo. to receive therapy, year 1Budget impact, year 1 (million USD)PMPM cost, year 1% change in year 1 PMPM cost from original model 6 PMPM cost, year 5
United States  7742 8.5 542 $1241.0 $1.13 18% $0.75 
Alabama 338 29.2 24 $54.2 $3.90 49% $2.60 
Washington, DC 69 23.6 $11.0 $3.15 45% $2.10 
Florida 904 18.7 63 $144.9 $2.50 41% $1.67 
Georgia 720 29.3 50 $115.4 $3.92 57% $2.61 
Louisiana 445 23.7 31 $71.4 $3.17 46% $2.11 
Maryland 329 19.7 23 $52.8 $2.63 59% $1.75 
Mississippi 203 26.5 14 $32.5 $3.55 –4% $2.36 
North Carolina 409 18.1 29 $65.5 $2.41 28% $1.60 
South Carolina 350 27.1 25 $56.1 $3.62 43% $2.42 
Virginia 339 17.2 24 $54.4 $2.30 20% $1.54 
Sample average 411 21.9 29 $65.8 $3.11 40% $2.08 

USD, US dollar.

Percent change in the year 1 PMPM impact when comparing the original model with the current and updated results.6 

The United States indicates all state Medicaid plans in aggregate.

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