Laboratory parameters at presentation of iTTP
| Laboratory parameters (NR) . | |
|---|---|
| Hemoglobin: median (range), mean (age-adjusted NR g/L, 105-135 for 2-y-old; up to 120-160 for 17-y-old) | 76 (42-104), 75.6 |
| Reticulocytes: absolute (range), mean (20-100 × 109/L) | 245 (110-347), 223.8 |
| Reticulocytes: % (range), mean | 4.95 (2.3-33.5), 10.3 |
| Platelet count: median (range), mean (×109/L) (150-450 × 109/L) | 10.5 (3-27), 11.6 |
| Cardiac troponin I: median (range), mean, ng/L (<34 ng/L) | 157 (14-164), 111.7 |
| Cardiac troponin T: median (range), mean, ng/L (14 mg/L) | 31.5 (4-1782), 183.6 |
| Urea: median (range), mean (age-adjusted NR mmol/L, 2.5- 6.0 for 2-y-old; up to 2.5-7.5 for 17-y-old) | 5.7 (2.7-11.8), 6.7 |
| Serum creatinine: median (range), mean, (age-adjusted NR umol/L, 15-31 for 2-y-old; up to 48-81 for 17-y-old) | 69 (38-146), 74.8 |
| Bilirubin: median (range), mean, (age-adjusted NR ug/mL, 15-31 for 2-y-old; up to 48-81 for 17-y-old) | 44 (2-85), 44.6 |
| LDH: median (range), mean (IU/L), (age-adjusted NR ug/mL, 500-920 for 2-y-old; up to 130-250 for 17-y-old) | 1344 (249-2353), 1350.8 |
| ADAMTS13 activity: median (range), mean (IU/dL) | 0 (0-10), 1.5 |
| ADAMTS13 inhibitor: median (range), mean (IU/dL) | 55 (11-135), 56.9 |
| Laboratory parameters (NR) . | |
|---|---|
| Hemoglobin: median (range), mean (age-adjusted NR g/L, 105-135 for 2-y-old; up to 120-160 for 17-y-old) | 76 (42-104), 75.6 |
| Reticulocytes: absolute (range), mean (20-100 × 109/L) | 245 (110-347), 223.8 |
| Reticulocytes: % (range), mean | 4.95 (2.3-33.5), 10.3 |
| Platelet count: median (range), mean (×109/L) (150-450 × 109/L) | 10.5 (3-27), 11.6 |
| Cardiac troponin I: median (range), mean, ng/L (<34 ng/L) | 157 (14-164), 111.7 |
| Cardiac troponin T: median (range), mean, ng/L (14 mg/L) | 31.5 (4-1782), 183.6 |
| Urea: median (range), mean (age-adjusted NR mmol/L, 2.5- 6.0 for 2-y-old; up to 2.5-7.5 for 17-y-old) | 5.7 (2.7-11.8), 6.7 |
| Serum creatinine: median (range), mean, (age-adjusted NR umol/L, 15-31 for 2-y-old; up to 48-81 for 17-y-old) | 69 (38-146), 74.8 |
| Bilirubin: median (range), mean, (age-adjusted NR ug/mL, 15-31 for 2-y-old; up to 48-81 for 17-y-old) | 44 (2-85), 44.6 |
| LDH: median (range), mean (IU/L), (age-adjusted NR ug/mL, 500-920 for 2-y-old; up to 130-250 for 17-y-old) | 1344 (249-2353), 1350.8 |
| ADAMTS13 activity: median (range), mean (IU/dL) | 0 (0-10), 1.5 |
| ADAMTS13 inhibitor: median (range), mean (IU/dL) | 55 (11-135), 56.9 |
All patients had red cell fragmentation identified on blood films at presentation.
LDH, lactate dehydrogenase; NR, normal range.