Table 2.

Health care costs per phase of life

Frail patients (n = 2 699),
median cost (IQR)
Nonfrail patients (n = 2 828),
median cost (IQR)
Total (N = 5 527),
median cost (IQR)
P value
By phase, costs standardized to per 30-d period 
Phase 1: pretreatment phase (90 d before the start of frontline treatment) 5 683 (3 065-10 322) 2 586 (1 656-4 721) 3 794 (2 073-7 355) <.0001 
Phase 2: initial treatment phase (start of frontline treatment plus 90 d) 13 090 (10 385-16 809) 11 256 (9 107-13 976) 12 077 (9 576-15 248) <.0001 
Phase 3: late treatment phase (90 d from start of frontline treatment to 180 d from start of frontline treatment) 5 734 (3 347-8 904) 4 883 (2 845-7 543) 5 256 (3 059-8 168) <.0001 
Phase 4: follow-up phase (end of treatment phase to the beginning of the end-of-life phase) 1 138 (552-2 397) 686 (350-1 425) 856 (425-1 850) <.0001 
Phase 5: end-of-life phase (final 180 d of life) 11 413 (5 845-21 381) 9 089 (4 844-15 793) 10 099 (5 384-18 874) <.0001 
Frail patients (n = 2 699),
median cost (IQR)
Nonfrail patients (n = 2 828),
median cost (IQR)
Total (N = 5 527),
median cost (IQR)
P value
By phase, costs standardized to per 30-d period 
Phase 1: pretreatment phase (90 d before the start of frontline treatment) 5 683 (3 065-10 322) 2 586 (1 656-4 721) 3 794 (2 073-7 355) <.0001 
Phase 2: initial treatment phase (start of frontline treatment plus 90 d) 13 090 (10 385-16 809) 11 256 (9 107-13 976) 12 077 (9 576-15 248) <.0001 
Phase 3: late treatment phase (90 d from start of frontline treatment to 180 d from start of frontline treatment) 5 734 (3 347-8 904) 4 883 (2 845-7 543) 5 256 (3 059-8 168) <.0001 
Phase 4: follow-up phase (end of treatment phase to the beginning of the end-of-life phase) 1 138 (552-2 397) 686 (350-1 425) 856 (425-1 850) <.0001 
Phase 5: end-of-life phase (final 180 d of life) 11 413 (5 845-21 381) 9 089 (4 844-15 793) 10 099 (5 384-18 874) <.0001 

Phase 1, the median duration was 90 days (IQR, 90-90; N = 5527). Phase 2, the median duration was 91 days (IQR, 91-91; n = 4631). Phase 3, the median duration was 90 days (IQR, 90-90; n = 4358). Phase 4, the median duration was 1412 days (IQR, 631-2513; n = 4112). Phase 5, the median duration was 181 days (IQR, 122-181; n = 3044).

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