Baseline characteristics
| Characteristics . | Frail (n = 2699), n (%) . | Nonfrail (n = 2828), n (%) . | Total (N = 5527), n (%) . | P value . |
|---|---|---|---|---|
| Age, median (IQR), y | 76 (71-81) | 74 (70-79) | 75 (70-80) | <.001 |
| Male | 1377 (51.0%) | 1478 (52.3%) | 2855 (51.7%) | .355 |
| Female | 1322 (49.0%) | 1350 (47.7%) | 2672 (48.3%) | |
| Era of treatment | .0003 | |||
| 2006-2009 | 890 (33.0%) | 976 (34.5%) | 1866 (33.8%) | |
| 2010-2013 | 816 (30.2%) | 954 (33.7%) | 1770 (32.0%) | |
| 2014-2017 | 993 (36.8%) | 898 (31.8%) | 1891 (34.2%) | |
| Neighborhood income quintile | ||||
| Q1 (lowest) | 552 (20.5%) | 351 (12.4%) | 903 (16.3%) | <.001 |
| Q2 | 676 (25.0%) | 481 (17.0%) | 1157 (20.9%) | |
| Q3 | 581 (21.5%) | 518 (18.3%) | 1099 (19.9%) | |
| Q4 | 432 (16.0%) | 680 (24.0%) | 1112 (20.1%) | |
| Q5 (highest) | 454 (16.8%) | 791 (28.0%) | 1245 (22.5%) | |
| Neighborhood-level educational attainment (census 2006) | ||||
| Missing/unknown | 206 (7.6%) | 242 (8.6%) | 448 (8.1%) | <.001 |
| Q1 (lowest) | 418 (15.5%) | 585 (20.7%) | 1003 (18.1%) | |
| Q2 | 489 (18.1%) | 528 (18.7%) | 1017 (18.4%) | |
| Q3 | 543 (20.1%) | 535 (18.9%) | 1078 (19.5%) | |
| Q4 | 531 (19.7%) | 496 (17.5%) | 1027 (18.6%) | |
| Q5 (highest) | 512 (19.0%) | 442 (15.6%) | 954 (17.3%) | |
| Rural dwelling | ||||
| Rural | 414 (15.3%) | 359 (12.7%) | 773 (14.0%) | <.005 |
| Urban | 2285 (84.7%) | 2469 (87.3%) | 4754 (86.0%) | |
| Number of ADG comorbidities∗ | ||||
| Median ADGs (IQR) | 13 (12-15) | 10 (8-12) | 12 (9-14) | <.001 |
| Cancer type | ||||
| DLBCL | 2558 (94.8%) | 2658 (94.0%) | 5216 (94.4%) | .204 |
| Transformed FL | 141 (5.2%) | 170 (6.0%) | 311 (5.6%) | |
| Status at time of diagnosis | ||||
| Inpatient | 756 (28.0%) | 450 (15.9%) | 1206 (21.8%) | <.001 |
| Outpatient | 1943 (72.0%) | 2378 (84.1%) | 4321 (78.2%) | |
| Cancer stage | ||||
| Missing/unknown† | 1476 (54.7%) | 1420 (50.2%) | 2896 (52.4%) | <.0001 |
| I | 233 (8.6%) | 349 (12.3%) | 582 (10.5%) | |
| II | 257 (9.5%) | 348 (12.3%) | 605 (10.9%) | |
| III | 233 (8.6%) | 283 (10.0%) | 516 (9.3%) | |
| IV | 500 (18.5%) | 428 (15.1%) | 928 (16.8%) |
| Characteristics . | Frail (n = 2699), n (%) . | Nonfrail (n = 2828), n (%) . | Total (N = 5527), n (%) . | P value . |
|---|---|---|---|---|
| Age, median (IQR), y | 76 (71-81) | 74 (70-79) | 75 (70-80) | <.001 |
| Male | 1377 (51.0%) | 1478 (52.3%) | 2855 (51.7%) | .355 |
| Female | 1322 (49.0%) | 1350 (47.7%) | 2672 (48.3%) | |
| Era of treatment | .0003 | |||
| 2006-2009 | 890 (33.0%) | 976 (34.5%) | 1866 (33.8%) | |
| 2010-2013 | 816 (30.2%) | 954 (33.7%) | 1770 (32.0%) | |
| 2014-2017 | 993 (36.8%) | 898 (31.8%) | 1891 (34.2%) | |
| Neighborhood income quintile | ||||
| Q1 (lowest) | 552 (20.5%) | 351 (12.4%) | 903 (16.3%) | <.001 |
| Q2 | 676 (25.0%) | 481 (17.0%) | 1157 (20.9%) | |
| Q3 | 581 (21.5%) | 518 (18.3%) | 1099 (19.9%) | |
| Q4 | 432 (16.0%) | 680 (24.0%) | 1112 (20.1%) | |
| Q5 (highest) | 454 (16.8%) | 791 (28.0%) | 1245 (22.5%) | |
| Neighborhood-level educational attainment (census 2006) | ||||
| Missing/unknown | 206 (7.6%) | 242 (8.6%) | 448 (8.1%) | <.001 |
| Q1 (lowest) | 418 (15.5%) | 585 (20.7%) | 1003 (18.1%) | |
| Q2 | 489 (18.1%) | 528 (18.7%) | 1017 (18.4%) | |
| Q3 | 543 (20.1%) | 535 (18.9%) | 1078 (19.5%) | |
| Q4 | 531 (19.7%) | 496 (17.5%) | 1027 (18.6%) | |
| Q5 (highest) | 512 (19.0%) | 442 (15.6%) | 954 (17.3%) | |
| Rural dwelling | ||||
| Rural | 414 (15.3%) | 359 (12.7%) | 773 (14.0%) | <.005 |
| Urban | 2285 (84.7%) | 2469 (87.3%) | 4754 (86.0%) | |
| Number of ADG comorbidities∗ | ||||
| Median ADGs (IQR) | 13 (12-15) | 10 (8-12) | 12 (9-14) | <.001 |
| Cancer type | ||||
| DLBCL | 2558 (94.8%) | 2658 (94.0%) | 5216 (94.4%) | .204 |
| Transformed FL | 141 (5.2%) | 170 (6.0%) | 311 (5.6%) | |
| Status at time of diagnosis | ||||
| Inpatient | 756 (28.0%) | 450 (15.9%) | 1206 (21.8%) | <.001 |
| Outpatient | 1943 (72.0%) | 2378 (84.1%) | 4321 (78.2%) | |
| Cancer stage | ||||
| Missing/unknown† | 1476 (54.7%) | 1420 (50.2%) | 2896 (52.4%) | <.0001 |
| I | 233 (8.6%) | 349 (12.3%) | 582 (10.5%) | |
| II | 257 (9.5%) | 348 (12.3%) | 605 (10.9%) | |
| III | 233 (8.6%) | 283 (10.0%) | 516 (9.3%) | |
| IV | 500 (18.5%) | 428 (15.1%) | 928 (16.8%) |