Table 3.

Assessment of IgRT among patients diagnosed with CLL and NHL receiving 1 or more IgRT during follow-up

CharacteristicsCLL (n = 259)NHL (n = 623)
Year of first IgRT, n (%)   
2010-2015 14 (12.5) 18 (6.1) 
2016-2020 59 (52.7) 166 (56.7) 
2021-2023 39 (34.8) 109 (37.2) 
Number of IgRT   
Mean ± SD 5.5 ± 8.8 4.9 ± 10.0 
Median (IQR) 2.0 (1.0-4.0) 2.0 (1.0-4.0) 
Number of IgRT, n (%) (1, 47) (1, 101) 
112 (43.2) 293 (47.0) 
40 (15.4) 112 (18.0) 
25 (9.7) 47 (7.5) 
21 (8.1) 40 (6.4) 
8 (3.1) 16 (2.6) 
8 (3.1) 17 (2.7) 
1 (0.4) 13 (2.1) 
≥8 44 (17.0) 85 (13.6) 
Patients with at least 1 IgG test, n (%) 244 (94.2) 584 (93.7) 
Serum IgG level closest to IgRT initiation (mg/dL), n (%)   
<200 39 (16.0) 93 (15.9) 
≥200 to <400 80 (32.8) 238 (40.8) 
≥400 to <500 29 (11.9) 54 (9.2) 
≥500 to <600 34 (13.9) 37 (6.3) 
≥600 62 (25.4) 162 (27.7) 
Patients with at least 1 IgG test before IgRT initiation, n (%) 215 (83.0) 516 (82.8) 
Time from last IgG test to IgRT initiation, mo   
Mean ± SD 6.5 ± 16.3 2.5 ± 9.9 
Median (IQR) 0.6 (0.1-3.5) 0.2 (0.1-1.0) 
Serum IgG level, mg/dL   
Mean ± SD 462.0 ± 359.0 455.2 ± 415.0 
Median (IQR) 369.0 (255.0-545.0) 356.5 (248.0-502.5) 
Patients with ≥2 IgRT, n (%) 147 (56.8) 330 (53.0) 
Time from first IgRT to subsequent IgG testing, mo   
Mean ± SD 6.3 ± 10.6 3.7 ± 7.8 
Median (IQR) 1.6 (0.7-7.0) 1.0 (0.3-3.0) 
CharacteristicsCLL (n = 259)NHL (n = 623)
Year of first IgRT, n (%)   
2010-2015 14 (12.5) 18 (6.1) 
2016-2020 59 (52.7) 166 (56.7) 
2021-2023 39 (34.8) 109 (37.2) 
Number of IgRT   
Mean ± SD 5.5 ± 8.8 4.9 ± 10.0 
Median (IQR) 2.0 (1.0-4.0) 2.0 (1.0-4.0) 
Number of IgRT, n (%) (1, 47) (1, 101) 
112 (43.2) 293 (47.0) 
40 (15.4) 112 (18.0) 
25 (9.7) 47 (7.5) 
21 (8.1) 40 (6.4) 
8 (3.1) 16 (2.6) 
8 (3.1) 17 (2.7) 
1 (0.4) 13 (2.1) 
≥8 44 (17.0) 85 (13.6) 
Patients with at least 1 IgG test, n (%) 244 (94.2) 584 (93.7) 
Serum IgG level closest to IgRT initiation (mg/dL), n (%)   
<200 39 (16.0) 93 (15.9) 
≥200 to <400 80 (32.8) 238 (40.8) 
≥400 to <500 29 (11.9) 54 (9.2) 
≥500 to <600 34 (13.9) 37 (6.3) 
≥600 62 (25.4) 162 (27.7) 
Patients with at least 1 IgG test before IgRT initiation, n (%) 215 (83.0) 516 (82.8) 
Time from last IgG test to IgRT initiation, mo   
Mean ± SD 6.5 ± 16.3 2.5 ± 9.9 
Median (IQR) 0.6 (0.1-3.5) 0.2 (0.1-1.0) 
Serum IgG level, mg/dL   
Mean ± SD 462.0 ± 359.0 455.2 ± 415.0 
Median (IQR) 369.0 (255.0-545.0) 356.5 (248.0-502.5) 
Patients with ≥2 IgRT, n (%) 147 (56.8) 330 (53.0) 
Time from first IgRT to subsequent IgG testing, mo   
Mean ± SD 6.3 ± 10.6 3.7 ± 7.8 
Median (IQR) 1.6 (0.7-7.0) 1.0 (0.3-3.0) 

SD, standard deviation.

The closest IgG test to IgRT initiation was used, either before or after IgRT initiation.

The last IgG test before IgRT imitation was used.

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