Best responses to therapy
| . | VCD (n = 57) . | VCDD (n = 64) . | P value . | ||
|---|---|---|---|---|---|
| % . | 95% CI . | % . | 95% CI . | ||
| OR (PR or better) | 64.91 | 51.13-77.09 | 85.94 | 74.98-93.36 | .007 |
| CR/sCR | 3.51 | 0.43-12.11 | 6.25 | 1.73-15.24 | .488 |
| ≥VGPR | 28.07 | 16.97-41.54 | 51.56 | 38.73-64.25 | .009 |
| MR | 10.53 | 3.96-21.52 | 6.25 | 1.73-15.24 | .394 |
| SD | 12.28 | 5.08-23.68 | 0.00 | 0.00-5.60 | .004 |
| PD | 1.75 | 0.04-9.39 | 0.00 | 0.00-5.60 | .287 |
| MRD-negative∗ | 5.26 | 1.10-14.62 | 15.63 | 7.76-26.86 | .066 |
| . | VCD (n = 57) . | VCDD (n = 64) . | P value . | ||
|---|---|---|---|---|---|
| % . | 95% CI . | % . | 95% CI . | ||
| OR (PR or better) | 64.91 | 51.13-77.09 | 85.94 | 74.98-93.36 | .007 |
| CR/sCR | 3.51 | 0.43-12.11 | 6.25 | 1.73-15.24 | .488 |
| ≥VGPR | 28.07 | 16.97-41.54 | 51.56 | 38.73-64.25 | .009 |
| MR | 10.53 | 3.96-21.52 | 6.25 | 1.73-15.24 | .394 |
| SD | 12.28 | 5.08-23.68 | 0.00 | 0.00-5.60 | .004 |
| PD | 1.75 | 0.04-9.39 | 0.00 | 0.00-5.60 | .287 |
| MRD-negative∗ | 5.26 | 1.10-14.62 | 15.63 | 7.76-26.86 | .066 |
MR, minimal response; PD, progressive disease; SD, stable disease.
Patients not known to be MRD-negative, with a missing value, either through a missing or suboptimal sample, are assumed to be MRD-positive.