Patient Characteristics
| . | VCD . | VCDD . |
|---|---|---|
| n | 57 | 64 |
| Age | ||
| Median (range), y | 75.4 (62-89) | 75.9 (64-91) |
| Distribution, no (%) | ||
| <70 y | 8 (14.0) | 9 (14.1) |
| ≥70 y to <75 y | 16 (28.1) | 20 (31.3) |
| ≥75 y to <80 y | 24 (42.1) | 22 (34.4) |
| ≥80 y | 9 (15.8) | 13 (20.3) |
| Sex (% male) | 59.7% | 76.6% |
| ECOG Performance Status, n (%) | ||
| 0 | 26 (45.6) | 26 (40.6) |
| 1 | 20 (35.1) | 24 (37.5) |
| ≥2 | 10 (17.5) | 13 (20.4) |
| Not known | 1 (1.8) | 1 (1.6) |
| Revised-ISS Stage, n (%) | ||
| Stage I | 6 (10.5) | 8 (12.5) |
| Stage II | 44 (77.2) | 41 (64.1) |
| Stage III | 3 (5.3) | 9 (14.1) |
| Not known | 4 (7.0) | 6 (9.4) |
| Cytogenetics | ||
| Standard risk | 43 (75.4) | 42 (65.6) |
| High risk | 7 (12.3) | 12 (18.8) |
| Not known | 7 (12.3) | 10 (15.6) |
| Renal function | ||
| Median eGFR | 65.2 mL/min | 75.2 mL/min |
| Distribution, n (%) | ||
| ≥60 mL/min | 34 (59.6) | 42 (65.6) |
| ≥45 and <60 mL/min | 9 (15.8) | 12 (18.8) |
| ≥30 and <45 mL/min | 13 (22.8) | 6 (9.4) |
| <30 mL/min | 1 (1.8) | 4 (6.2) |
| IMWG Frailty Score, n (%) | ||
| Frail | 11 (19.3) | 13 (20.3) |
| Intermediate | 23 (40.4) | 22 (34.4) |
| Fit | 23 (40.4) | 29 (45.3) |
| . | VCD . | VCDD . |
|---|---|---|
| n | 57 | 64 |
| Age | ||
| Median (range), y | 75.4 (62-89) | 75.9 (64-91) |
| Distribution, no (%) | ||
| <70 y | 8 (14.0) | 9 (14.1) |
| ≥70 y to <75 y | 16 (28.1) | 20 (31.3) |
| ≥75 y to <80 y | 24 (42.1) | 22 (34.4) |
| ≥80 y | 9 (15.8) | 13 (20.3) |
| Sex (% male) | 59.7% | 76.6% |
| ECOG Performance Status, n (%) | ||
| 0 | 26 (45.6) | 26 (40.6) |
| 1 | 20 (35.1) | 24 (37.5) |
| ≥2 | 10 (17.5) | 13 (20.4) |
| Not known | 1 (1.8) | 1 (1.6) |
| Revised-ISS Stage, n (%) | ||
| Stage I | 6 (10.5) | 8 (12.5) |
| Stage II | 44 (77.2) | 41 (64.1) |
| Stage III | 3 (5.3) | 9 (14.1) |
| Not known | 4 (7.0) | 6 (9.4) |
| Cytogenetics | ||
| Standard risk | 43 (75.4) | 42 (65.6) |
| High risk | 7 (12.3) | 12 (18.8) |
| Not known | 7 (12.3) | 10 (15.6) |
| Renal function | ||
| Median eGFR | 65.2 mL/min | 75.2 mL/min |
| Distribution, n (%) | ||
| ≥60 mL/min | 34 (59.6) | 42 (65.6) |
| ≥45 and <60 mL/min | 9 (15.8) | 12 (18.8) |
| ≥30 and <45 mL/min | 13 (22.8) | 6 (9.4) |
| <30 mL/min | 1 (1.8) | 4 (6.2) |
| IMWG Frailty Score, n (%) | ||
| Frail | 11 (19.3) | 13 (20.3) |
| Intermediate | 23 (40.4) | 22 (34.4) |
| Fit | 23 (40.4) | 29 (45.3) |
ECOG, Eastern Cooperative Oncology Group; eGFR, estimated glomerular filtration rate; IMWG, International Myeloma Working Group; ISS, International Staging System.