Univariable analysis of transplant outcomes according to donor type
| Outcome . | MUD . | MMUD . | Haploidentical . | P value . |
|---|---|---|---|---|
| Myeloid engraftment, CI at 28 d (%) | 85 (83-87) | 84 (80-88) | 75 (69-81) | .033 |
| Platelet engraftment, CI at 100 d (%) | 88 (86-91) | 82 (78-87) | 72 (65-78) | <.001 |
| PGF, CI at 42 d (%) | 3 (2-4) | 7 (4-10) | 13 (8-17) | <.001 |
| SGF, 3-y CI (%) | 4 (3-5) | 4 (2-7) | 2 (0-4) | .4 |
| aGVHD grades 2-4, CI at 100 d (%) | 13 (11-15) | 22 (17-27) | 19 (13-24) | <.001 |
| aGVHD grades 3-4, CI at 100 d (%) | 5 (3-6) | 9 (5-12) | 7 (3-10) | .028 |
| Overall cGVHD, 3-y CI (%) | 18 (16-21) | 20 (15-25) | 18 (11-25) | .79 |
| Extensive cGVHD, 3-y CI (%) | 7 (6-9) | 7 (4-10) | 6 (1-10) | .6 |
| NRM, 3-y CI (%) | 14 (12-17) | 19 (14-23) | 27 (19-34) | <.001 |
| EFS, 3-y CI (%) | 73 (71-76) | 63 (58-69) | 55 (47-63) | <.001 |
| OS, 3-y CI (%) | 81 (79-84) | 74 (69-79) | 63 (54-71) | <.001 |
| GRFS, 3-y CI (%) | 73 (70-76) | 65 (60-71) | 54 (45-62) | <.001 |
| Outcome . | MUD . | MMUD . | Haploidentical . | P value . |
|---|---|---|---|---|
| Myeloid engraftment, CI at 28 d (%) | 85 (83-87) | 84 (80-88) | 75 (69-81) | .033 |
| Platelet engraftment, CI at 100 d (%) | 88 (86-91) | 82 (78-87) | 72 (65-78) | <.001 |
| PGF, CI at 42 d (%) | 3 (2-4) | 7 (4-10) | 13 (8-17) | <.001 |
| SGF, 3-y CI (%) | 4 (3-5) | 4 (2-7) | 2 (0-4) | .4 |
| aGVHD grades 2-4, CI at 100 d (%) | 13 (11-15) | 22 (17-27) | 19 (13-24) | <.001 |
| aGVHD grades 3-4, CI at 100 d (%) | 5 (3-6) | 9 (5-12) | 7 (3-10) | .028 |
| Overall cGVHD, 3-y CI (%) | 18 (16-21) | 20 (15-25) | 18 (11-25) | .79 |
| Extensive cGVHD, 3-y CI (%) | 7 (6-9) | 7 (4-10) | 6 (1-10) | .6 |
| NRM, 3-y CI (%) | 14 (12-17) | 19 (14-23) | 27 (19-34) | <.001 |
| EFS, 3-y CI (%) | 73 (71-76) | 63 (58-69) | 55 (47-63) | <.001 |
| OS, 3-y CI (%) | 81 (79-84) | 74 (69-79) | 63 (54-71) | <.001 |
| GRFS, 3-y CI (%) | 73 (70-76) | 65 (60-71) | 54 (45-62) | <.001 |
Univariable outcomes of engraftment, graft failure, acute and cGVHD, NRM, OS, EFS, GVHD, and GRFS, stratified by donor type. Kaplan–Meier estimates of OS, EFS, and GRFS are given, with group differences tested by log-rank tests, and cumulative incidences are given for all other outcomes, with group differences tested by the Gray test. All estimates are reported with 95% CIs in parentheses.