Multivariate analysis of predictors of thromboembolism in patients with PNH
| Variable . | OR . | Low 95% CI . | High 95% CI . | P value . |
|---|---|---|---|---|
| AST >40 U/L | 0.73 | 0.25 | 2.02 | .5434 |
| ALT >40 U/L | 1.79 | 0.66 | 4.81 | .2472 |
| Albumin <4.2 g/dL | 0.49 | 0.21 | 1.11 | .0911 |
| D-dimers >1000 mg/L | 1.96 | 0.54 | 7.19 | .3026 |
| Reticulocytes >80 × 103/μL | 1.05 | 0.39 | 2.76 | .9271 |
| ANC <1.5 × 109/L | 0.82 | 0.32 | 2.13 | .6881 |
| Platelets <100 × 109/L | 0.69 | 0.25 | 1.93 | .4859 |
| LDH >400 U/L | 2.84 | 1.01 | 8.30 | .0514 |
| Type II–dominant RBC PNH | 4.09 | 1.32 | 13.19 | .0160 |
| RBC clonal size >20% | 0.70 | 0.22 | 2.16 | .5438 |
| Granulocyte clonal size >70% | 2.05 | 0.77 | 5.56 | .1536 |
| PIGA VAF >15% | 2.59 | 0.72 | 10.44 | .1600 |
| Variable . | OR . | Low 95% CI . | High 95% CI . | P value . |
|---|---|---|---|---|
| AST >40 U/L | 0.73 | 0.25 | 2.02 | .5434 |
| ALT >40 U/L | 1.79 | 0.66 | 4.81 | .2472 |
| Albumin <4.2 g/dL | 0.49 | 0.21 | 1.11 | .0911 |
| D-dimers >1000 mg/L | 1.96 | 0.54 | 7.19 | .3026 |
| Reticulocytes >80 × 103/μL | 1.05 | 0.39 | 2.76 | .9271 |
| ANC <1.5 × 109/L | 0.82 | 0.32 | 2.13 | .6881 |
| Platelets <100 × 109/L | 0.69 | 0.25 | 1.93 | .4859 |
| LDH >400 U/L | 2.84 | 1.01 | 8.30 | .0514 |
| Type II–dominant RBC PNH | 4.09 | 1.32 | 13.19 | .0160 |
| RBC clonal size >20% | 0.70 | 0.22 | 2.16 | .5438 |
| Granulocyte clonal size >70% | 2.05 | 0.77 | 5.56 | .1536 |
| PIGA VAF >15% | 2.59 | 0.72 | 10.44 | .1600 |
ALT, alanine aminotransferase.
Bold indicates statistical significance.