Examples of 1-, 2-, and 3-year relapse-risk prediction for patients with pedAML using the nomogram prediction model
| AMLlnc69 . | NPM mutation . | WBC at diagnosis . | 1-y risk, % (95% CI) . | 2-y risk, % (95% CI) . | 3-y risk, % (95% CI) . |
|---|---|---|---|---|---|
| High | No | ≥50 | 56.8 (48.3-63.8) | 80.5 (72.9-86.0) | 83.6 (76.4-88.7) |
| High | Yes | ≥50 | 29.8 (14.2-42.6) | 49.9 (26.1-66.0) | 53.4 (28.5-69.7) |
| High | No | <50 | 49.2 (42.1-55.5) | 73.3 (66.1-79.0) | 76.8 (69.8-82.2) |
| High | Yes | <50 | 24.9 (11.7-36.2) | 42.8 (21.7-58.2) | 46.1 (23.8-61.9) |
| Low | No | ≥50 | 18.1 (13.8-22.3) | 32.3 (25.6-38.4) | 35.1 (28.0-41.4) |
| Low | Yes | ≥50 | 8.1 (3.7-12.4) | 15.2 (7.2-22.5) | 16.7 (7.9-24.6) |
| Low | No | <50 | 14.9 (11.9-17.9) | 27.1 (22.5-31.4) | 29.5 (24.7-34.0) |
| Low | Yes | <50 | 6.6 (3.0-10.0) | 12.5 (6.0-18.5) | 13.7 (6.6-20.3) |
| AMLlnc69 . | NPM mutation . | WBC at diagnosis . | 1-y risk, % (95% CI) . | 2-y risk, % (95% CI) . | 3-y risk, % (95% CI) . |
|---|---|---|---|---|---|
| High | No | ≥50 | 56.8 (48.3-63.8) | 80.5 (72.9-86.0) | 83.6 (76.4-88.7) |
| High | Yes | ≥50 | 29.8 (14.2-42.6) | 49.9 (26.1-66.0) | 53.4 (28.5-69.7) |
| High | No | <50 | 49.2 (42.1-55.5) | 73.3 (66.1-79.0) | 76.8 (69.8-82.2) |
| High | Yes | <50 | 24.9 (11.7-36.2) | 42.8 (21.7-58.2) | 46.1 (23.8-61.9) |
| Low | No | ≥50 | 18.1 (13.8-22.3) | 32.3 (25.6-38.4) | 35.1 (28.0-41.4) |
| Low | Yes | ≥50 | 8.1 (3.7-12.4) | 15.2 (7.2-22.5) | 16.7 (7.9-24.6) |
| Low | No | <50 | 14.9 (11.9-17.9) | 27.1 (22.5-31.4) | 29.5 (24.7-34.0) |
| Low | Yes | <50 | 6.6 (3.0-10.0) | 12.5 (6.0-18.5) | 13.7 (6.6-20.3) |
CI, confidence interval.