Table 3.

Health care utilization specifically for HHT or VWD management in women with HHT vs VWD

HHT
N = 100
VWD
N = 100
P value 
ED visits and hospital admissions specifically for HHT or VWD management 
Requirement for ED visit, n (%) 25 (25) 8 (8) .001  
ED visits, per 100 patient-years 10.3 0.74 .001 
Requirement for hospital admission, n (%) 50 (50) 12 (12) <.0001  
Hospital admissions, per 100 patient-years 14.4 1.0 <.0001 
Length of hospital stay, mean (range) 5.5 (1-28) 4.3 (1-15) .47 
Outpatient encounters§ specifically for HHT or VWD management 
Any outpatient encounter, per 100 patient-years 386.5 43.7 <.0001 
Primary care provider, per 100 patient-years 37.9 19.1 .28 
Hematology, per 100 patient-years 62.3 11.3 .005 
Pulmonology, per 100 patient-years 36.5 0.1 <.0001 
Cardiology, per 100 patient-years 4.3 0.9 .005 
Gastroenterology, per 100 patient-years 14.7 0.9 <.0001 
Otolaryngology, per 100 patient-years 18.3 0.7 <.0001 
Obstetrics and gynecology, per 100 patient-years 4.4 5.9 .003 
Medical Genetics, per 100 patient-years 7.7 0.0 <.0001 
Dermatology, per 100 patient-years 5.1 0.0 .003 
Outpatient infusion, per 100 patient-years 97.6 5.3 <.0001 
Radiology/imaging, per 100 patient-years 74.0 0.3 <.0001 
Other, per 100 patient-years 23.3 1.3 <.0001 
HHT
N = 100
VWD
N = 100
P value 
ED visits and hospital admissions specifically for HHT or VWD management 
Requirement for ED visit, n (%) 25 (25) 8 (8) .001  
ED visits, per 100 patient-years 10.3 0.74 .001 
Requirement for hospital admission, n (%) 50 (50) 12 (12) <.0001  
Hospital admissions, per 100 patient-years 14.4 1.0 <.0001 
Length of hospital stay, mean (range) 5.5 (1-28) 4.3 (1-15) .47 
Outpatient encounters§ specifically for HHT or VWD management 
Any outpatient encounter, per 100 patient-years 386.5 43.7 <.0001 
Primary care provider, per 100 patient-years 37.9 19.1 .28 
Hematology, per 100 patient-years 62.3 11.3 .005 
Pulmonology, per 100 patient-years 36.5 0.1 <.0001 
Cardiology, per 100 patient-years 4.3 0.9 .005 
Gastroenterology, per 100 patient-years 14.7 0.9 <.0001 
Otolaryngology, per 100 patient-years 18.3 0.7 <.0001 
Obstetrics and gynecology, per 100 patient-years 4.4 5.9 .003 
Medical Genetics, per 100 patient-years 7.7 0.0 <.0001 
Dermatology, per 100 patient-years 5.1 0.0 .003 
Outpatient infusion, per 100 patient-years 97.6 5.3 <.0001 
Radiology/imaging, per 100 patient-years 74.0 0.3 <.0001 
Other, per 100 patient-years 23.3 1.3 <.0001 

All P values are per the Wilcoxon rank-sum test (except those marked with the symbol).

Includes only ED visits in which the patient was discharged from the ED without hospital admission. ED visits ending at hospital admission were counted only once, as hospital admissions.

P values are per χ2 test.

§

All outpatient encounters except for outpatient infusion and radiology/imaging were face-to-face visits with a clinician (physician, nurse practitioner, or physician assistant).

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