Serum concentrations (pg/mL) of cytokines between patients with TAM with or without early death
| . | Patients with early death, n = 14 . | Patients without early death, n = 114 . | P value∗ . |
|---|---|---|---|
| IL-1b, median (range) | 4.435 (1.94-351.1) | 2.630 (0.63-3662) | .031 |
| IL-1ra | 372.1 (101.9-1544) | 122.0 (8.85-9285) | .007 |
| IL-4 | 4.690 (1.69-9.35) | 3.725 (0.89-32.97) | .178 |
| IL-5 | 5.210 (0.26-20.88) | 2.140 (0.06-17.35) | .232 |
| IL-6 | 222.9 (23.55-1537) | 37.43 (1.75-6851) | .022 |
| IL-7 | 31.30 (4.43-613.2) | 12.86 (0.97-301.1) | .081 |
| IL-8 | 217.1 (28.92-8350) | 45.87 (8.81-37418) | .004 |
| IL-9 | 34.92 (2.46-110.2) | 23.43 (1.26-250.6) | .335 |
| IL-10 | 28.38 (1.85-260.5) | 11.71 (1.56-170.6) | .069 |
| IL-13 | 22.80 (3.52-173.5) | 9.045 (0.58-199.2) | .037 |
| Eotaxin | 178.2 (46.17-2265) | 150.4 (12.50-892.0) | .424 |
| PDGF-bb | 5755 (300.0-18523) | 4568 (61.75-18489) | .434 |
| Basic FGF | 60.28 (19.26-935.3) | 49.75 (6.77-254.3) | .261 |
| G-CSF | 58.34 (25.63-7232) | 56.40 (9.39-1770) | .354 |
| GM-CSF | 141.7 (59.65-851.1) | 138.1 (6.05-1836) | .750 |
| IFN-r | 106.4 (26.36-597.9) | 74.79 (10.22-6328) | .329 |
| IP-10 | 1360 (195.7-17268) | 1857 (70.84-18686) | .604 |
| MCP-1(MCAF) | 658.6 (93.37-4051) | 292.3 (31.28-10398) | .222 |
| MIP-1a | 7.79 (2.63-759.1) | 6.660 (0.53-565.6) | .347 |
| MIP-1b | 454.5 (116.8-50908) | 283.8 (59.98-40790) | .185 |
| TNF-a | 63.46 (21.97-362.8) | 40.66 (10.23-1029) | .065 |
| VEGF | 105.7 (12.17-1974) | 76.85 (8.27-4490) | .275 |
| . | Patients with early death, n = 14 . | Patients without early death, n = 114 . | P value∗ . |
|---|---|---|---|
| IL-1b, median (range) | 4.435 (1.94-351.1) | 2.630 (0.63-3662) | .031 |
| IL-1ra | 372.1 (101.9-1544) | 122.0 (8.85-9285) | .007 |
| IL-4 | 4.690 (1.69-9.35) | 3.725 (0.89-32.97) | .178 |
| IL-5 | 5.210 (0.26-20.88) | 2.140 (0.06-17.35) | .232 |
| IL-6 | 222.9 (23.55-1537) | 37.43 (1.75-6851) | .022 |
| IL-7 | 31.30 (4.43-613.2) | 12.86 (0.97-301.1) | .081 |
| IL-8 | 217.1 (28.92-8350) | 45.87 (8.81-37418) | .004 |
| IL-9 | 34.92 (2.46-110.2) | 23.43 (1.26-250.6) | .335 |
| IL-10 | 28.38 (1.85-260.5) | 11.71 (1.56-170.6) | .069 |
| IL-13 | 22.80 (3.52-173.5) | 9.045 (0.58-199.2) | .037 |
| Eotaxin | 178.2 (46.17-2265) | 150.4 (12.50-892.0) | .424 |
| PDGF-bb | 5755 (300.0-18523) | 4568 (61.75-18489) | .434 |
| Basic FGF | 60.28 (19.26-935.3) | 49.75 (6.77-254.3) | .261 |
| G-CSF | 58.34 (25.63-7232) | 56.40 (9.39-1770) | .354 |
| GM-CSF | 141.7 (59.65-851.1) | 138.1 (6.05-1836) | .750 |
| IFN-r | 106.4 (26.36-597.9) | 74.79 (10.22-6328) | .329 |
| IP-10 | 1360 (195.7-17268) | 1857 (70.84-18686) | .604 |
| MCP-1(MCAF) | 658.6 (93.37-4051) | 292.3 (31.28-10398) | .222 |
| MIP-1a | 7.79 (2.63-759.1) | 6.660 (0.53-565.6) | .347 |
| MIP-1b | 454.5 (116.8-50908) | 283.8 (59.98-40790) | .185 |
| TNF-a | 63.46 (21.97-362.8) | 40.66 (10.23-1029) | .065 |
| VEGF | 105.7 (12.17-1974) | 76.85 (8.27-4490) | .275 |
Bold indicates P < 0.05.
G-CSF, granulocyte colony-stimulating factor; GM-CSF, granulocyte-macrophage colony-stimulating factor; MCAF, monocyte chemotactic and activating factor; MCP-1, monocyte chemoattractant protein-1; MIP, macrophage inflammatory protein; PDGF, platelet-derived growth factor; TNF-a, tumor necrosis factor-alpha; VEGF, vascular endothelial growth factor.
P value was evaluated using the Mann-Whitney U test, followed by the Benjamini-Hochberg method used as a correction for multiple testing.