Patient and donor characteristics
Patient and disease characteristics . | No. of patients (n = 9) . |
---|---|
Median age, (range), y | 43 (29-62) |
Sex, n | |
Male | 5 (56%) |
Female | 4 (44%) |
Diagnosis, n | |
SPTCL | 5 (56%) |
Skin only | 2 (23%) |
Extracutaneous site∗ | 3 (33%) |
Primary CGDTCL | 4 (44%) |
Skin only | 2 (22%) |
Extracutaneous site∗ | 2 (22%) |
History of HLH | |
Yes | 7 (78%) |
No | 2 (22%) |
Time from diagnosis to allogeneic HCT, median (range), mo | 10.7 (6.7-44.9) |
<24 mo | 8 (88%) |
≥24 mo | 1 (12%) |
No. of prior systemic therapies, median (range) | 3 (1-7) |
Disease status at the time of conditioning, n | |
CR | 4 (44%) |
PR | 4 (44%) |
SD | 1 (12%) |
Targeted radiation before conditioning | |
Yes | 4 (44%) |
No | 5 (56%) |
Donor, n | |
HLA-matched sibling | 3 (33%) |
Haploidentical | 2 (23%) |
Unrelated | 4 (44%) |
Matched | 2 (22%) |
Mismatched† | 2 (22%) |
Patient and disease characteristics . | No. of patients (n = 9) . |
---|---|
Median age, (range), y | 43 (29-62) |
Sex, n | |
Male | 5 (56%) |
Female | 4 (44%) |
Diagnosis, n | |
SPTCL | 5 (56%) |
Skin only | 2 (23%) |
Extracutaneous site∗ | 3 (33%) |
Primary CGDTCL | 4 (44%) |
Skin only | 2 (22%) |
Extracutaneous site∗ | 2 (22%) |
History of HLH | |
Yes | 7 (78%) |
No | 2 (22%) |
Time from diagnosis to allogeneic HCT, median (range), mo | 10.7 (6.7-44.9) |
<24 mo | 8 (88%) |
≥24 mo | 1 (12%) |
No. of prior systemic therapies, median (range) | 3 (1-7) |
Disease status at the time of conditioning, n | |
CR | 4 (44%) |
PR | 4 (44%) |
SD | 1 (12%) |
Targeted radiation before conditioning | |
Yes | 4 (44%) |
No | 5 (56%) |
Donor, n | |
HLA-matched sibling | 3 (33%) |
Haploidentical | 2 (23%) |
Unrelated | 4 (44%) |
Matched | 2 (22%) |
Mismatched† | 2 (22%) |