Demographic and clinical characteristics by group
| Characteristic . | m1: steep decline with recovery . | m2: slight decline . | m3: slight improvement/stable . | m4: early improvement, later decline . |
|---|---|---|---|---|
| Group size, n (%) | 8 (2.4) | 141 (40.8) | 153 (45.0) | 41 (11.8) |
| Age at baseline, mean (SD; range), y | 69 (6.2; 59.9-80.1) | 65 (13.4; 19.7-88.2) | 66 (11.0; 35.9-100.3) | 58 (15.3; 28.3-82.3) |
| Gender, n (%) | ||||
| Female | 5 (62.5) | 59 (41.8) | 43 (28.1) | 24 (58.5) |
| Male | 3 (37.5) | 82 (58.2) | 110 (71.9) | 17 (41.5) |
| Race, n (%) | ||||
| Other | 16 (11.3) | 13 (8.5) | 4 (9.8) | |
| White | 8 (100.0) | 125 (88.7) | 140 (91.5) | 37 (90.2) |
| Marital status, n (%) | ||||
| Single, divorced or widowed | 3 (37.5) | 37 (26.2) | 34 (22.2) | 13 (31.7) |
| Married | 5 (62.5) | 104 (73.8) | 119 (77.8) | 28 (68.3) |
| Education, n (%) | ||||
| Some college or less | 3 (37.5) | 76 (53.9) | 69 (45.1) | 14 (34.1) |
| College graduate | 5 (62.5) | 65 (46.1) | 84 (54.9) | 27 (65.9) |
| Income∗, n (%) | ||||
| Missing | 2 (25.0) | 15 (10.6) | 8 (5.2) | 4 (9.8) |
| <25 000 | 1 (12.5) | 16 (11.4) | 12 (7.8) | 5 (12.2) |
| $25 000-$50 000 | 2 (25.0) | 31 (22.0) | 35 (22.9) | 6 (14.6) |
| $50 000-$100 000 | 2 (25.0) | 38 (27.0) | 50 (32.7) | 14 (34.2) |
| >100 000 | 1 (12.5) | 41 (29.1) | 48 (31.4) | 12 (29.3) |
| AML disease risk, n (%) | ||||
| Favorable risk | 0 (0.0) | 9 (6.4) | 18 (11.8) | 5 (12.2) |
| Intermediate risk | 3 (37.5) | 81 (57.4) | 77 (50.3) | 17 (41.5) |
| Adverse risk | 5 (62.5) | 51 (36.2) | 58 (37.9) | 19 (46.3) |
| Treatment regimen, n (%) | ||||
| Intensive | 8 (100.0) | 97 (68.8) | 107 (69.9) | 32 (78.0) |
| Lower intensity | 0 (0.0) | 44 (31.2) | 46 (30.1) | 9 (22.0) |
| HADS Depression Score, mean (SD, range) | 5 (2.6, 1-8) | 4 (3.3, 0-18) | 6 (3.7, 0-17) | 9 (4.1, 1-17) |
| HADS Anxiety Score, mean (SD, range) | 3 (2.4, 0-7) | 5 (4.0, 0-17) | 6 (3.8, 0-20) | 8 (4.8, 0-17) |
| FACT-PWB, mean (SD, range) | 24 (3.3, 18-28) | 24 (3.2, 14-28) | 19 (4.3, 8-27) | 10 (3.8, 2-17) |
| Vital status at last follow-up, n (%) | ||||
| Alive | 2 (25.0) | 54 (38.3) | 68 (44.4) | 17 (41.5) |
| Deceased | 6 (75.0) | 86 (61.0) | 83 (54.2) | 24 (58.5) |
| Unknown | 0 (0.0) | 1 (0.7) | 2 (1.3) | 0 (0.0) |
| Characteristic . | m1: steep decline with recovery . | m2: slight decline . | m3: slight improvement/stable . | m4: early improvement, later decline . |
|---|---|---|---|---|
| Group size, n (%) | 8 (2.4) | 141 (40.8) | 153 (45.0) | 41 (11.8) |
| Age at baseline, mean (SD; range), y | 69 (6.2; 59.9-80.1) | 65 (13.4; 19.7-88.2) | 66 (11.0; 35.9-100.3) | 58 (15.3; 28.3-82.3) |
| Gender, n (%) | ||||
| Female | 5 (62.5) | 59 (41.8) | 43 (28.1) | 24 (58.5) |
| Male | 3 (37.5) | 82 (58.2) | 110 (71.9) | 17 (41.5) |
| Race, n (%) | ||||
| Other | 16 (11.3) | 13 (8.5) | 4 (9.8) | |
| White | 8 (100.0) | 125 (88.7) | 140 (91.5) | 37 (90.2) |
| Marital status, n (%) | ||||
| Single, divorced or widowed | 3 (37.5) | 37 (26.2) | 34 (22.2) | 13 (31.7) |
| Married | 5 (62.5) | 104 (73.8) | 119 (77.8) | 28 (68.3) |
| Education, n (%) | ||||
| Some college or less | 3 (37.5) | 76 (53.9) | 69 (45.1) | 14 (34.1) |
| College graduate | 5 (62.5) | 65 (46.1) | 84 (54.9) | 27 (65.9) |
| Income∗, n (%) | ||||
| Missing | 2 (25.0) | 15 (10.6) | 8 (5.2) | 4 (9.8) |
| <25 000 | 1 (12.5) | 16 (11.4) | 12 (7.8) | 5 (12.2) |
| $25 000-$50 000 | 2 (25.0) | 31 (22.0) | 35 (22.9) | 6 (14.6) |
| $50 000-$100 000 | 2 (25.0) | 38 (27.0) | 50 (32.7) | 14 (34.2) |
| >100 000 | 1 (12.5) | 41 (29.1) | 48 (31.4) | 12 (29.3) |
| AML disease risk, n (%) | ||||
| Favorable risk | 0 (0.0) | 9 (6.4) | 18 (11.8) | 5 (12.2) |
| Intermediate risk | 3 (37.5) | 81 (57.4) | 77 (50.3) | 17 (41.5) |
| Adverse risk | 5 (62.5) | 51 (36.2) | 58 (37.9) | 19 (46.3) |
| Treatment regimen, n (%) | ||||
| Intensive | 8 (100.0) | 97 (68.8) | 107 (69.9) | 32 (78.0) |
| Lower intensity | 0 (0.0) | 44 (31.2) | 46 (30.1) | 9 (22.0) |
| HADS Depression Score, mean (SD, range) | 5 (2.6, 1-8) | 4 (3.3, 0-18) | 6 (3.7, 0-17) | 9 (4.1, 1-17) |
| HADS Anxiety Score, mean (SD, range) | 3 (2.4, 0-7) | 5 (4.0, 0-17) | 6 (3.8, 0-20) | 8 (4.8, 0-17) |
| FACT-PWB, mean (SD, range) | 24 (3.3, 18-28) | 24 (3.2, 14-28) | 19 (4.3, 8-27) | 10 (3.8, 2-17) |
| Vital status at last follow-up, n (%) | ||||
| Alive | 2 (25.0) | 54 (38.3) | 68 (44.4) | 17 (41.5) |
| Deceased | 6 (75.0) | 86 (61.0) | 83 (54.2) | 24 (58.5) |
| Unknown | 0 (0.0) | 1 (0.7) | 2 (1.3) | 0 (0.0) |
HADS, Hospital Anxiety and Depression Scale.
∗Annual, in United States dollars.