CPSS-Mol genetic risk group
| Variable score points . | CPSS cytogenetic risk group . | ASXL1 . | NRAS . | RUNX1 . | SETBP1 . |
|---|---|---|---|---|---|
| 0 | Normal karyotype, isolated -Y | Unmutated | Unmutated | Unmutated | Unmutated |
| 1 | All other abnormalities | Mutated | Mutated | — | Mutated |
| 2 | Trisomy 8, complex karyotype (≥3 abnormalities), abnormalities of chromosome 7 | — | — | Mutated | — |
| Variable score points . | CPSS cytogenetic risk group . | ASXL1 . | NRAS . | RUNX1 . | SETBP1 . |
|---|---|---|---|---|---|
| 0 | Normal karyotype, isolated -Y | Unmutated | Unmutated | Unmutated | Unmutated |
| 1 | All other abnormalities | Mutated | Mutated | — | Mutated |
| 2 | Trisomy 8, complex karyotype (≥3 abnormalities), abnormalities of chromosome 7 | — | — | Mutated | — |
| Genetic risk group category . | |
|---|---|
| Total score points . | CPSS genetic risk group . |
| 0 | Low |
| 1 | Intermediate-1 |
| 2 | Intermediate-2 |
| ≥3 | High |
| Genetic risk group category . | |
|---|---|
| Total score points . | CPSS genetic risk group . |
| 0 | Low |
| 1 | Intermediate-1 |
| 2 | Intermediate-2 |
| ≥3 | High |
Adapted from Elena et al.48
-Y, loss of chromosome Y.