Results in adult Ph-like ALL
| Study . | Age group (y) . | Total patients and frequency of Ph-like ALL in B-other∗ . | 5-year survival (EFS or OS) . |
|---|---|---|---|
| Roberts et al, 2014162 | 16-20 | 77 (21%) | EFS 41%, OS 66% |
| 21-39 | 46 (27%) | EFS 24%, OS 26% | |
| Herold et al, 2014163 | 16-20 | 5 (19%) | |
| 21-39 | 12 (18%) | DFS (all ages) 19% | |
| 40-55 | 4 (9%) | OS (all ages) 22% | |
| 55-84 | 5 (7%) | ||
| Boer et al, 2015159 | 16-20 | 6 (25%) | EFS (all ages) 24% |
| 21-39 | 9 (19%) | OS (all ages) 30% | |
| 40-71 | 6 (11%) | ||
| Jain et al, 2017164 | 15-39 | 33 (42%) | |
| 40-84 | 16 (24%) | OS (all ages) 23% | |
| Roberts et al, 2017165 | 21-39 | 96 (28%) | EFS 24% |
| 40-59 | 62 (20%) | EFS 21% | |
| 60-86 | 36 (24%) | EFS 8% | |
| Chiaretti et al, 2018161 | 0-15 | 2 (9%) | EFS (excluding children) 22% |
| 15-35 | 29 (29%) | OS (excluding children) 37% | |
| 35 | 23 (31%) | ||
| Stock et al, 20196 | 17-39 | 41 (31%) | OS (3 y), 63% |
| Chiaretti et al, 2021166 | 18-65 | 28 (32%) | EFS (2 y), 34% |
| OS (2 y), 40% |
| Study . | Age group (y) . | Total patients and frequency of Ph-like ALL in B-other∗ . | 5-year survival (EFS or OS) . |
|---|---|---|---|
| Roberts et al, 2014162 | 16-20 | 77 (21%) | EFS 41%, OS 66% |
| 21-39 | 46 (27%) | EFS 24%, OS 26% | |
| Herold et al, 2014163 | 16-20 | 5 (19%) | |
| 21-39 | 12 (18%) | DFS (all ages) 19% | |
| 40-55 | 4 (9%) | OS (all ages) 22% | |
| 55-84 | 5 (7%) | ||
| Boer et al, 2015159 | 16-20 | 6 (25%) | EFS (all ages) 24% |
| 21-39 | 9 (19%) | OS (all ages) 30% | |
| 40-71 | 6 (11%) | ||
| Jain et al, 2017164 | 15-39 | 33 (42%) | |
| 40-84 | 16 (24%) | OS (all ages) 23% | |
| Roberts et al, 2017165 | 21-39 | 96 (28%) | EFS 24% |
| 40-59 | 62 (20%) | EFS 21% | |
| 60-86 | 36 (24%) | EFS 8% | |
| Chiaretti et al, 2018161 | 0-15 | 2 (9%) | EFS (excluding children) 22% |
| 15-35 | 29 (29%) | OS (excluding children) 37% | |
| 35 | 23 (31%) | ||
| Stock et al, 20196 | 17-39 | 41 (31%) | OS (3 y), 63% |
| Chiaretti et al, 2021166 | 18-65 | 28 (32%) | EFS (2 y), 34% |
| OS (2 y), 40% |
B-other: Ph negative without other defining molecular abnormalities (eg, KMT2A, low hypodiploid, hyperdiploid).