Table 2.

Summary of conclusions based on in vitro, animal model and clinical correlative analysis

In vitro analysisAnimal model resultsClinical correlative results
T cells in the TME contribute to RTX-induced NK-cell viability and activation ✓ ✓ ✓ 
T-cell help enhances RTX-mediated target cell lysis ✓ ✓  
T-cell help enhances the antitumor activity of RTX  ✓  
In vitro analysisAnimal model resultsClinical correlative results
T cells in the TME contribute to RTX-induced NK-cell viability and activation ✓ ✓ ✓ 
T-cell help enhances RTX-mediated target cell lysis ✓ ✓  
T-cell help enhances the antitumor activity of RTX  ✓  

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