Table 1.

Genes of the p53 score

Gene symbolGene nameCytogenetic location
APOBEC3C Apolipoprotein B mRNA–editing enzyme catalytic subunit 3C 22q13.1 
APOBEC3H Apolipoprotein B mRNA–editing enzyme catalytic subunit 3H 22q13.1 
BAX BCL2-associated X 19q13.33 
CDKN1A Cyclin-dependent kinase inhibitor 1A 6p21.2 
DDB2 Damage-specific DNA-binding protein 2 11p11.2 
EDA2R Ectodysplasin A2 receptor Xq12 
FDXR Ferredoxin reductase 17q25.1 
MDM2 MDM2 proto-oncogene 12q15 
PHLDA3 Pleckstrin homology–like domain family A member 3 1q32.1 
RPS27L Ribosomal protein S27 like 15q22.2 
RRM2B Ribonucleotide reductase regulatory TP53–inducible subunit M2B 8q22.3 
TIGAR TP53-induced glycolysis regulatory phosphatase 12p13.32 
TNFRSF10B TNF receptor superfamily member 10b 8p21.3 
Gene symbolGene nameCytogenetic location
APOBEC3C Apolipoprotein B mRNA–editing enzyme catalytic subunit 3C 22q13.1 
APOBEC3H Apolipoprotein B mRNA–editing enzyme catalytic subunit 3H 22q13.1 
BAX BCL2-associated X 19q13.33 
CDKN1A Cyclin-dependent kinase inhibitor 1A 6p21.2 
DDB2 Damage-specific DNA-binding protein 2 11p11.2 
EDA2R Ectodysplasin A2 receptor Xq12 
FDXR Ferredoxin reductase 17q25.1 
MDM2 MDM2 proto-oncogene 12q15 
PHLDA3 Pleckstrin homology–like domain family A member 3 1q32.1 
RPS27L Ribosomal protein S27 like 15q22.2 
RRM2B Ribonucleotide reductase regulatory TP53–inducible subunit M2B 8q22.3 
TIGAR TP53-induced glycolysis regulatory phosphatase 12p13.32 
TNFRSF10B TNF receptor superfamily member 10b 8p21.3 

The table indicates the name and chromosomal location of the 13 genes involved in the score.

mRNA, messenger RNA; TNF, tumor necrosis factor.

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