Baseline characteristics and prior thrombosis
| Baseline characteristics . | Number (%) . |
|---|---|
| Mean age at diagnosis | 43 years and 11 months |
| Male | 237 (46.6) |
| Median granulocyte clone at diagnosis | 78.3% |
| Documented history of aplastic anemia | 215 (42.2) |
| Documented history of myelodysplastic syndrome | 31 (6.1) |
| History of thrombosis | 205 thromboses in 135 patients (26.5) |
| Thromboses before complement inhibition | |
| Budd-Chiari | 53 |
| Cerebrovascular accident and transient ischemic attack | 33 |
| Mesenteric and splenic | 27 |
| Myocardial infarction | 23 |
| Pulmonary embolus | 22 |
| Deep vein thrombosis | 20 |
| Cerebral venous thrombosis | 14 |
| Catheter related | 3 |
| Dermal | 3 |
| Limb ischemia | 3 |
| Retinal | 2 |
| Internal jugular | 1 |
| Esopageal ischemia | 1 |
| Baseline characteristics . | Number (%) . |
|---|---|
| Mean age at diagnosis | 43 years and 11 months |
| Male | 237 (46.6) |
| Median granulocyte clone at diagnosis | 78.3% |
| Documented history of aplastic anemia | 215 (42.2) |
| Documented history of myelodysplastic syndrome | 31 (6.1) |
| History of thrombosis | 205 thromboses in 135 patients (26.5) |
| Thromboses before complement inhibition | |
| Budd-Chiari | 53 |
| Cerebrovascular accident and transient ischemic attack | 33 |
| Mesenteric and splenic | 27 |
| Myocardial infarction | 23 |
| Pulmonary embolus | 22 |
| Deep vein thrombosis | 20 |
| Cerebral venous thrombosis | 14 |
| Catheter related | 3 |
| Dermal | 3 |
| Limb ischemia | 3 |
| Retinal | 2 |
| Internal jugular | 1 |
| Esopageal ischemia | 1 |