Baseline characteristics
| . | HGBL-MYC/BCL2 . | DLBCL NOS . | P value . |
|---|---|---|---|
| (n = 66) . | (n = 53) . | ||
| Age, y | |||
| Mean (SD) | 60.2 (9.78) | 67.0 (11.2) | <.001 |
| Median (min, max) | 62.0 (35.0, 79.0) | 68.0 (32.0, 88.0) | |
| Sex | |||
| Male | 42 (63.6%) | 28 (52.8%) | .32 |
| Female | 24 (36.4%) | 25 (47.2%) | |
| WHO performance score | |||
| 0 | 43 (65.2%) | 26 (49.1%) | .048 |
| 1 | 19 (28.8%) | 15 (28.3%) | |
| 2 | 4 (6.1%) | 10 (18.9%) | |
| 3 | 0 (0%) | 2 (3.8%) | |
| LDH level | |||
| Within normal range | 21 (31.8%) | 23 (43.4%) | .27 |
| Elevated | 45 (68.2%) | 30 (56.6%) | |
| Extranodal localizations (number) | |||
| None | 25 (37.9%) | 20 (37.7%) | .5 |
| 1 | 14 (21.2%) | 14 (26.4%) | |
| ≥2 | 26 (39.4%) | 14 (26.4%) | |
| Unknown | 1 (1.5%) | 5 (9.4%) | |
| IPI score | |||
| Low | 8 (12.1%) | 11 (20.8%) | .04 |
| Low-intermediate | 28 (42.2%) | 15 (28.3%) | |
| High-intermediate | 24 (36.4%) | 14 (26.4%) | |
| High | 6 (9.1%) | 9 (17.0%) | |
| Missing | 0 (0%) | 4 (7.5%) | |
| MYC-rearrangement | |||
| No | 53 (100%) | ||
| Yes | 66 (100%) | ||
| DH/TH status | |||
| HGBL: BCL2 DH | 52 (78.8%) | ||
| HGBL: TH | 14 (21.2%) | ||
| DLBCL NOS | 53 (100%) |
| . | HGBL-MYC/BCL2 . | DLBCL NOS . | P value . |
|---|---|---|---|
| (n = 66) . | (n = 53) . | ||
| Age, y | |||
| Mean (SD) | 60.2 (9.78) | 67.0 (11.2) | <.001 |
| Median (min, max) | 62.0 (35.0, 79.0) | 68.0 (32.0, 88.0) | |
| Sex | |||
| Male | 42 (63.6%) | 28 (52.8%) | .32 |
| Female | 24 (36.4%) | 25 (47.2%) | |
| WHO performance score | |||
| 0 | 43 (65.2%) | 26 (49.1%) | .048 |
| 1 | 19 (28.8%) | 15 (28.3%) | |
| 2 | 4 (6.1%) | 10 (18.9%) | |
| 3 | 0 (0%) | 2 (3.8%) | |
| LDH level | |||
| Within normal range | 21 (31.8%) | 23 (43.4%) | .27 |
| Elevated | 45 (68.2%) | 30 (56.6%) | |
| Extranodal localizations (number) | |||
| None | 25 (37.9%) | 20 (37.7%) | .5 |
| 1 | 14 (21.2%) | 14 (26.4%) | |
| ≥2 | 26 (39.4%) | 14 (26.4%) | |
| Unknown | 1 (1.5%) | 5 (9.4%) | |
| IPI score | |||
| Low | 8 (12.1%) | 11 (20.8%) | .04 |
| Low-intermediate | 28 (42.2%) | 15 (28.3%) | |
| High-intermediate | 24 (36.4%) | 14 (26.4%) | |
| High | 6 (9.1%) | 9 (17.0%) | |
| Missing | 0 (0%) | 4 (7.5%) | |
| MYC-rearrangement | |||
| No | 53 (100%) | ||
| Yes | 66 (100%) | ||
| DH/TH status | |||
| HGBL: BCL2 DH | 52 (78.8%) | ||
| HGBL: TH | 14 (21.2%) | ||
| DLBCL NOS | 53 (100%) |
LDH, lactate dehydrogenase; TH, triple hit.