Response rates and hematologic values in patients receiving rEPO vs the comparison population
| . | rEPO (N = 47) . | No rEPO (N = 43) . |
|---|---|---|
| Baseline | ||
| Hb g/dL, mean (SD) | 7.6 (1.7) | 7.8 (1.4) |
| Transfusions (%) | 14 (30) | 15 (35) |
| 15 d | 47 | 43 |
| ORR (%) - CR/PR∗ | 26 (55) - 3/23 | 14 (32) - 1/3 |
| Hb g/dL, mean (SD)∗ | 9.5 (1.5) | 8.8 (1.5) |
| Transfusions (%) | 4 (9) | 7 (15) |
| 1 mo | 47 | 43 |
| ORR (%) - CR/PR | 35 (74) - 10/25 | 25 (58) - 4/21 |
| Hb g/dL, mean (SD)∗ | 10.5 (1.9) | 9.8 (1.5) |
| Transfusions (%) | 3 (6) | 4 (9) |
| 3 mo | 47 | 43 |
| ORR (%) - CR/PR | 35 (74) - 19/16 | 30 (69)- 12/18 |
| Hb g/dL, mean (SD) | 11.2 (1.9) | 10.8 (1.9) |
| Transfusions (%) | 2 (4) | 1 (2) |
| 6 mo | 44 | 42 |
| ORR (%) - CR/PR | 35 (80) - 22/13 | 30 (71) - 13/17 |
| Hb g/dL, mean (SD) | 11.3 (2.1) | 10.8 (1.8) |
| Transfusions (%) | 3 (7) | 2 (5) |
| 12 mo | 34 | 39 |
| ORR (%) - CR/PR | 31 (91) - 25/6 | 29 (74) - 13/16 |
| Hb g/dL, mean (SD) | 12.1 (1.4) | 11.1 (2) |
| Transfusions (%) | 0 (0) | 1 (3) |
| . | rEPO (N = 47) . | No rEPO (N = 43) . |
|---|---|---|
| Baseline | ||
| Hb g/dL, mean (SD) | 7.6 (1.7) | 7.8 (1.4) |
| Transfusions (%) | 14 (30) | 15 (35) |
| 15 d | 47 | 43 |
| ORR (%) - CR/PR∗ | 26 (55) - 3/23 | 14 (32) - 1/3 |
| Hb g/dL, mean (SD)∗ | 9.5 (1.5) | 8.8 (1.5) |
| Transfusions (%) | 4 (9) | 7 (15) |
| 1 mo | 47 | 43 |
| ORR (%) - CR/PR | 35 (74) - 10/25 | 25 (58) - 4/21 |
| Hb g/dL, mean (SD)∗ | 10.5 (1.9) | 9.8 (1.5) |
| Transfusions (%) | 3 (6) | 4 (9) |
| 3 mo | 47 | 43 |
| ORR (%) - CR/PR | 35 (74) - 19/16 | 30 (69)- 12/18 |
| Hb g/dL, mean (SD) | 11.2 (1.9) | 10.8 (1.9) |
| Transfusions (%) | 2 (4) | 1 (2) |
| 6 mo | 44 | 42 |
| ORR (%) - CR/PR | 35 (80) - 22/13 | 30 (71) - 13/17 |
| Hb g/dL, mean (SD) | 11.3 (2.1) | 10.8 (1.8) |
| Transfusions (%) | 3 (7) | 2 (5) |
| 12 mo | 34 | 39 |
| ORR (%) - CR/PR | 31 (91) - 25/6 | 29 (74) - 13/16 |
| Hb g/dL, mean (SD) | 12.1 (1.4) | 11.1 (2) |
| Transfusions (%) | 0 (0) | 1 (3) |
CR, complete response; PR, partial response; SD, standard deviation.
P < .05.