Grade 3 or more treatment toxicities
Toxicity . | Grade . | N . | Percentage of whole population . | |
---|---|---|---|---|
Atrial fibrillation∗ | Unknown | 1 | 0.7% | 0.7% |
Bleeding | 4 | 2 | 1.3% | 4.0% |
3 | 2 | 1.3% | ||
Unknown | 2 | 1.3% | ||
Hepatic impairment | 3 | 1 | 0.7% | 0.7% |
Myelosuppression | 4 | 3 | 2.0% | 4.0% |
3 | 2 | 1.3% | ||
Unknown | 1 | 0.7% | ||
Neurological | 3 | 1 | 0.7% | 1.3% |
Unknown | 1 | 0.7% | ||
Nonneutropenic infection | 5 | 1 | 0.7% | 7.4% |
3 | 4 | 2.7% | ||
Unknown | 6 | 4.0% | ||
Pleural effusion | 3 | 2 | 1.3% | 1.3% |
Small bowel obstruction | Unknown | 1 | 0.7% | 0.7% |
Stroke | 5 | 1 | 0.7% | 1.3% |
3 | 1 | 0.7% |
Toxicity . | Grade . | N . | Percentage of whole population . | |
---|---|---|---|---|
Atrial fibrillation∗ | Unknown | 1 | 0.7% | 0.7% |
Bleeding | 4 | 2 | 1.3% | 4.0% |
3 | 2 | 1.3% | ||
Unknown | 2 | 1.3% | ||
Hepatic impairment | 3 | 1 | 0.7% | 0.7% |
Myelosuppression | 4 | 3 | 2.0% | 4.0% |
3 | 2 | 1.3% | ||
Unknown | 1 | 0.7% | ||
Neurological | 3 | 1 | 0.7% | 1.3% |
Unknown | 1 | 0.7% | ||
Nonneutropenic infection | 5 | 1 | 0.7% | 7.4% |
3 | 4 | 2.7% | ||
Unknown | 6 | 4.0% | ||
Pleural effusion | 3 | 2 | 1.3% | 1.3% |
Small bowel obstruction | Unknown | 1 | 0.7% | 0.7% |
Stroke | 5 | 1 | 0.7% | 1.3% |
3 | 1 | 0.7% |
In addition to 1 case of treatment-emergent grade 3 to 5 atrial fibrillation, there were 8 cases of grade 1 to 2 atrial fibrillation.