Patient characteristics
. | . | N . | % . |
---|---|---|---|
Age at ICI initiation | Median age | 40.1 y | |
<50 | 48 | 69.6 | |
50-59.9 | 7 | 10.1 | |
60-69.9 | 6 | 8.7 | |
70-79.9 | 5 | 7.2 | |
≥80 | 3 | 4.3 | |
Sex | Female | 33 | 47.8 |
Male | 36 | 52.2 | |
Histology | Nodular sclerosing | 59 | 85.5 |
Mixed cellularity | 3 | 4.3 | |
Classical NOS | 6 | 8.7 | |
Lymphocyte rich | 1 | 1.4 | |
Bulky | Yes | 21 | 30.4 |
No | 47 | 68.1 | |
Unknown | 1 | 1.4 | |
Extranodal disease | Yes | 29 | 42.0 |
No | 40 | 58.0 | |
Stage at diagnosis | I | 2 | 2.9 |
II | 23 | 33.3 | |
III | 15 | 21.7 | |
IV | 29 | 42.0 | |
Pre-ICI disease | Relapsed | 36 | 52.2 |
Refractory | 17 | 24.6 | |
First diagnosis | 16 | 23.2 | |
Previous ASCT | Yes | 50 | 72.5 |
No | 19 | 27.5 | |
Previous radiation | Yes | 30 | 43.5 |
No | 39 | 56.5 | |
ICIs used | Nivolumab | 54 | 78.3 |
Pembrolizumab | 12 | 17.4 | |
Other | 3 | 4.3 | |
Number of disease sites at ICI initiation | ≤5 sites | 45 | 65.2 |
>5 sites | 24 | 34.8 | |
Number of therapies before ICIs | Mean | 4.4 therapies | |
Q1, Q3 | 1, 6 | ||
Range | 0-16 |
. | . | N . | % . |
---|---|---|---|
Age at ICI initiation | Median age | 40.1 y | |
<50 | 48 | 69.6 | |
50-59.9 | 7 | 10.1 | |
60-69.9 | 6 | 8.7 | |
70-79.9 | 5 | 7.2 | |
≥80 | 3 | 4.3 | |
Sex | Female | 33 | 47.8 |
Male | 36 | 52.2 | |
Histology | Nodular sclerosing | 59 | 85.5 |
Mixed cellularity | 3 | 4.3 | |
Classical NOS | 6 | 8.7 | |
Lymphocyte rich | 1 | 1.4 | |
Bulky | Yes | 21 | 30.4 |
No | 47 | 68.1 | |
Unknown | 1 | 1.4 | |
Extranodal disease | Yes | 29 | 42.0 |
No | 40 | 58.0 | |
Stage at diagnosis | I | 2 | 2.9 |
II | 23 | 33.3 | |
III | 15 | 21.7 | |
IV | 29 | 42.0 | |
Pre-ICI disease | Relapsed | 36 | 52.2 |
Refractory | 17 | 24.6 | |
First diagnosis | 16 | 23.2 | |
Previous ASCT | Yes | 50 | 72.5 |
No | 19 | 27.5 | |
Previous radiation | Yes | 30 | 43.5 |
No | 39 | 56.5 | |
ICIs used | Nivolumab | 54 | 78.3 |
Pembrolizumab | 12 | 17.4 | |
Other | 3 | 4.3 | |
Number of disease sites at ICI initiation | ≤5 sites | 45 | 65.2 |
>5 sites | 24 | 34.8 | |
Number of therapies before ICIs | Mean | 4.4 therapies | |
Q1, Q3 | 1, 6 | ||
Range | 0-16 |
NOS, not otherwise specified.