Table 1. Survival and hazard ratios for... | American Society of Hematology

Table 1.

Survival and hazard ratios for thalassemia-related mortality according to pretransfusion hemoglobin level

Pretransfusion hemoglobin, g/dL∗	Deaths n (%)	Pearson’s χ² (P value)	5-year survival (%)	10-year survival (%)	Log-rank χ² (P value)	Unadjusted HR	95% CI (P value)	Adjusted HR†	95% CI (P value)
<9 (n = 43)	4 (9.3)	10.492 (.033)	93	91	11.370 (.025)	1.00 (referent)	—	1.00 (referent)	—
9 to <9.5 (n = 160)	8 (5.0)		96	95		0.506	0.162-1.681 (0.266)	0.563	0.165-1.919 (.358)
9.5 to 10 (n = 350)	9 (2.6)		99	97		0.256	0.079-0.830 (0.023)	0.248	0.074-0.832 (.024)
>10 to 10.5 (n = 183)	3 (1.6)		99	98		0.162	0.036-0.724 (0.017)	0.125	0.027-0.574 (.008)
≥10.5 (n = 43)	0 (0.0)		100	100		NC	NC	NC	NC

Pretransfusion hemoglobin, g/dL∗	Deaths n (%)	Pearson’s χ² (P value)	5-year survival (%)	10-year survival (%)	Log-rank χ² (P value)	Unadjusted HR	95% CI (P value)	Adjusted HR†	95% CI (P value)
<9 (n = 43)	4 (9.3)	10.492 (.033)	93	91	11.370 (.025)	1.00 (referent)	—	1.00 (referent)	—
9 to <9.5 (n = 160)	8 (5.0)		96	95		0.506	0.162-1.681 (0.266)	0.563	0.165-1.919 (.358)
9.5 to 10 (n = 350)	9 (2.6)		99	97		0.256	0.079-0.830 (0.023)	0.248	0.074-0.832 (.024)
>10 to 10.5 (n = 183)	3 (1.6)		99	98		0.162	0.036-0.724 (0.017)	0.125	0.027-0.574 (.008)
≥10.5 (n = 43)	0 (0.0)		100	100		NC	NC	NC	NC

Values in boldface indicate P < .05. NC, noncalculable.

Ten-year observation period average.

Adjusted for age at study start, center, sex, presence of active morbidity at baseline in a multivariate forward stepwise Cox regression model.