Table 3.

The performance of r-PET TLG in distinguishing R/R lymphoma from benign histology for different lymphoma subtypes

All cases
N = 271
Large B-cell lymphoma
N = 88
Indolent NHL
N = 101
HL
N = 44
ROC AUC 0.798 0.877 0.722 0.730 
P <.001 <.001 .002 .002 
Using optimal cut-off of the whole group: ≥245 
Sensitivity, specificity 63%, 86% 69%, 92% 64%, 60% 39%, 100% 
PPV, NPV 97%, 30% 94%, 46% 92%, 24% 100%, 41% 
Using optimal cut-off of the individual subgroups ≥220 ≥470 ≥160 
Sensitivity, specificity  71%, 92% 54%, 80% 52%, 92% 
PPV, NPV  92%, 44% 94%, 22% 94%, 43% 
All cases
N = 271
Large B-cell lymphoma
N = 88
Indolent NHL
N = 101
HL
N = 44
ROC AUC 0.798 0.877 0.722 0.730 
P <.001 <.001 .002 .002 
Using optimal cut-off of the whole group: ≥245 
Sensitivity, specificity 63%, 86% 69%, 92% 64%, 60% 39%, 100% 
PPV, NPV 97%, 30% 94%, 46% 92%, 24% 100%, 41% 
Using optimal cut-off of the individual subgroups ≥220 ≥470 ≥160 
Sensitivity, specificity  71%, 92% 54%, 80% 52%, 92% 
PPV, NPV  92%, 44% 94%, 22% 94%, 43% 
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