r-PET optimal threshold values to distinguish benign histology vs R/R lymphoma
| . | SUVMax . | SUVMean . | TMTV, ml . | TLG . | ||||
|---|---|---|---|---|---|---|---|---|
| Benign . | R/R lymphoma . | Benign . | R/R lymphoma . | Benign . | R/R lymphoma . | Benign . | R/R lymphoma . | |
| Median (IQR) | 8.8 (5.8-12.0) | 11.6 (7.5-18.7) | 4.0 (2.6-4.4) | 4.6 (3.3-7.0) | 19 (5-52) | 107 (32-333) | 79 (19-168) | 524 (136-2076) |
| ROC AUC | 0.668 | 0.649 | 0.782 | 0.798 | ||||
| P | <.001 | <.001 | <.001 | <.001 | ||||
| Optimal threshold | ≥13 | ≥4.5 | ≥90 | ≥245 | ||||
| Sensitivity, specificity | 43%, 86% | 51%, 79% | 54%, 86% | 63%, 86% | ||||
| PPV, NPV | 94%, 21% | 93%, 22% | 96%, 25% | 97%, 30% | ||||
| . | SUVMax . | SUVMean . | TMTV, ml . | TLG . | ||||
|---|---|---|---|---|---|---|---|---|
| Benign . | R/R lymphoma . | Benign . | R/R lymphoma . | Benign . | R/R lymphoma . | Benign . | R/R lymphoma . | |
| Median (IQR) | 8.8 (5.8-12.0) | 11.6 (7.5-18.7) | 4.0 (2.6-4.4) | 4.6 (3.3-7.0) | 19 (5-52) | 107 (32-333) | 79 (19-168) | 524 (136-2076) |
| ROC AUC | 0.668 | 0.649 | 0.782 | 0.798 | ||||
| P | <.001 | <.001 | <.001 | <.001 | ||||
| Optimal threshold | ≥13 | ≥4.5 | ≥90 | ≥245 | ||||
| Sensitivity, specificity | 43%, 86% | 51%, 79% | 54%, 86% | 63%, 86% | ||||
| PPV, NPV | 94%, 21% | 93%, 22% | 96%, 25% | 97%, 30% | ||||
IQR, interquartile range; ROC AUC, area under the curve in receive operative characteristic curve analysis; r-PET, FDG-PET at rebiopsy time point.