Disease relapse/progression
| Variables . | EUROCORD (N = 496) . | JSTCT (N = 1150) . | ||||
|---|---|---|---|---|---|---|
| HR . | 95% CI . | P value . | HR . | 95% CI . | P value . | |
| Age∗ (<50 or ≥50) | ||||||
| 18-49 | 1.00 | Reference | 1.00 | Reference | ||
| 50-70 | 0.58 | (0.38-0.88) | .010 | 0.82 | (0.65-1.04) | .103 |
| rDRI | ||||||
| Low | 1.00 | Reference | 1.00 | Reference | ||
| Intermediate | 1.48 | (0.98-2.24) | .064 | 2.01 | (1.11-3.67) | .022 |
| High or very high | 2.04 | (1.21-3.42) | .007 | 2.96 | (1.64-5.34) | <.001 |
| Conditioning | ||||||
| TBI-RIC | 1.00 | Reference | 1.00 | Reference | ||
| TBI-MAC | 0.77 | (0.39-1.53) | .461 | 0.83 | (0.62-1.11) | .204 |
| Non–TBI-RIC | 1.19 | (0.74-1.90) | .469 | 1.36 | (1.00-1.84) | .052 |
| Non–TBI-MAC | 0.67 | (0.35-1.30) | .234 | 1.05 | (0.68-1.62) | .817 |
| History of auto-HCT | ||||||
| No | 1.00 | Reference | 1.00 | Reference | ||
| Yes | 0.94 | (0.64-1.37) | .743 | 0.65 | (0.49-0.86) | .002 |
| Variables . | EUROCORD (N = 496) . | JSTCT (N = 1150) . | ||||
|---|---|---|---|---|---|---|
| HR . | 95% CI . | P value . | HR . | 95% CI . | P value . | |
| Age∗ (<50 or ≥50) | ||||||
| 18-49 | 1.00 | Reference | 1.00 | Reference | ||
| 50-70 | 0.58 | (0.38-0.88) | .010 | 0.82 | (0.65-1.04) | .103 |
| rDRI | ||||||
| Low | 1.00 | Reference | 1.00 | Reference | ||
| Intermediate | 1.48 | (0.98-2.24) | .064 | 2.01 | (1.11-3.67) | .022 |
| High or very high | 2.04 | (1.21-3.42) | .007 | 2.96 | (1.64-5.34) | <.001 |
| Conditioning | ||||||
| TBI-RIC | 1.00 | Reference | 1.00 | Reference | ||
| TBI-MAC | 0.77 | (0.39-1.53) | .461 | 0.83 | (0.62-1.11) | .204 |
| Non–TBI-RIC | 1.19 | (0.74-1.90) | .469 | 1.36 | (1.00-1.84) | .052 |
| Non–TBI-MAC | 0.67 | (0.35-1.30) | .234 | 1.05 | (0.68-1.62) | .817 |
| History of auto-HCT | ||||||
| No | 1.00 | Reference | 1.00 | Reference | ||
| Yes | 0.94 | (0.64-1.37) | .743 | 0.65 | (0.49-0.86) | .002 |
95% CI, 95% confidence interval; auto-HCT, autologous HCT.
Results of the analysis statistically significant (with P < .05) are highlighted in bold.
Indicates patients’ age at CBT.