Table 3.

Characteristics of patients with cGVHD of whom samples were used for protein microarray

PatientAge (y)Recipient sexDonor sex/relationshipGVHD prophylaxisPrior acute GVHD (grade)Organs affected by cGVHDMonths after HSCT at cGVHD onsetImmune suppression day of IgG studyCancer type
46 M/unrelated Rapamycin/ FK506 None Skin, mouth, eye (SICCA) Prednisone 15 mg, rapamycin, MMF NHL 
55 F/related CD8 depletion, FK506 None Skin 10 MMF ALL 
40 M/related Rapamycin/ FK506 None Mouth, eyes (SICCA), liver 10 FK506 IMF 
53 M/related Rapamycin/ FK506 None Skin, mouth, liver Prednisone 20 mg, rapamycin CML 
30 F/related Rapamycin/ FK506 Skin, liver None AML 
58 M/related CD8 depletion, FK506 Skin, mouth, lung None MDS/ AML 
45 F/unrelated Rapamycin/ FK506 Skin, mouth (scleroderma) Prednisone 15 mg, MMF AML 
50 M/related Rapamycin/ FK506 Liver, muscle None CML 
50 F/related CD8 depletion, FK506 Skin, mouth (scleroderma) 10 None CLL 
10 62 F/related Rapamycin/ FK506 Skin, mouth Rapamycin, FK506 CLL 
PatientAge (y)Recipient sexDonor sex/relationshipGVHD prophylaxisPrior acute GVHD (grade)Organs affected by cGVHDMonths after HSCT at cGVHD onsetImmune suppression day of IgG studyCancer type
46 M/unrelated Rapamycin/ FK506 None Skin, mouth, eye (SICCA) Prednisone 15 mg, rapamycin, MMF NHL 
55 F/related CD8 depletion, FK506 None Skin 10 MMF ALL 
40 M/related Rapamycin/ FK506 None Mouth, eyes (SICCA), liver 10 FK506 IMF 
53 M/related Rapamycin/ FK506 None Skin, mouth, liver Prednisone 20 mg, rapamycin CML 
30 F/related Rapamycin/ FK506 Skin, liver None AML 
58 M/related CD8 depletion, FK506 Skin, mouth, lung None MDS/ AML 
45 F/unrelated Rapamycin/ FK506 Skin, mouth (scleroderma) Prednisone 15 mg, MMF AML 
50 M/related Rapamycin/ FK506 Liver, muscle None CML 
50 F/related CD8 depletion, FK506 Skin, mouth (scleroderma) 10 None CLL 
10 62 F/related Rapamycin/ FK506 Skin, mouth Rapamycin, FK506 CLL 

ALL, acute lymphoblastic leukemia; AML, acute myeloid leukemia; CLL, chronic lymphocytic leukemia; CML, chronic myeloid leukemia; F, female; M, male; MDS, myelodysplastic syndrome; MMF, mycophenolate mofetil; NHL, non-Hodgkin lymphoma.

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