Table 4

Multivariable analysis for PFS for patients receiving a transplant and for all patients who had a MUD search

MeasureHR (95% CI)P
Multivariable analysis for PFS for patients receiving a transplant, N = 151   
Donor   
 Related (MRD/Haplotype) vs 10/10 MUD and 9/10 MUD 1.20 (0.62-2.33) .50 
Disease status at transplant   
 CR1/2 vs other 0.63 (0.37-1.08) .09 
Cytogenetics   
 Adverse vs intermediate/favorable 3.18 (1.87-5.43) <.0001 
Diagnosis   
 De novo AML vs other 0.39 (0.19-0.79) .009 
Time from MUD search to transplant, continuous 1.00 (1.00-1.01) .010 
Multivariable analysis for PFS for all patients who had a MUD search, N = 242 
Race   
 White vs other 0.98 (0.66-1.46) .92 
Disease status at MUD search   
 Remission/newly diagnosed vs other 0.52 (0.36-0.74) <.001 
Cytogenetics   
 Adverse vs intermediate/favorable 2.67 (1.87-3.83) <.0001 
Diagnosis   
 De novo AML vs other 0.40 (0.26-0.63) <.0001 
Haplotype frequency   
 Common vs uncommon 0.68 (0.45-1.02) .06 
Transplant   
 Yes vs no 0.32 (0.23-0.45) <.0001 
MeasureHR (95% CI)P
Multivariable analysis for PFS for patients receiving a transplant, N = 151   
Donor   
 Related (MRD/Haplotype) vs 10/10 MUD and 9/10 MUD 1.20 (0.62-2.33) .50 
Disease status at transplant   
 CR1/2 vs other 0.63 (0.37-1.08) .09 
Cytogenetics   
 Adverse vs intermediate/favorable 3.18 (1.87-5.43) <.0001 
Diagnosis   
 De novo AML vs other 0.39 (0.19-0.79) .009 
Time from MUD search to transplant, continuous 1.00 (1.00-1.01) .010 
Multivariable analysis for PFS for all patients who had a MUD search, N = 242 
Race   
 White vs other 0.98 (0.66-1.46) .92 
Disease status at MUD search   
 Remission/newly diagnosed vs other 0.52 (0.36-0.74) <.001 
Cytogenetics   
 Adverse vs intermediate/favorable 2.67 (1.87-3.83) <.0001 
Diagnosis   
 De novo AML vs other 0.40 (0.26-0.63) <.0001 
Haplotype frequency   
 Common vs uncommon 0.68 (0.45-1.02) .06 
Transplant   
 Yes vs no 0.32 (0.23-0.45) <.0001 
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