Baseline characteristics of spleen-intact controls and patients undergoing splenectomy
| Parameter . | Spleen-intact controls (n = 20) . | Patients undergoing splenectomy (n = 16) . | ||
|---|---|---|---|---|
| Day 0 . | Day 60 . | Day 360∗ . | ||
| Age, y | 28 (26-31) | 27 (17-35) | ||
| Males, % (n/N) | 40 (8/20) | 81 (13/16) | ||
| Papuan, % (n/N) | 95 (19/20) | 25 (4/16) | ||
| Splenectomy due to trauma, % (n/N) | — | 88 (14/16) | ||
| Platelet counts, ×103/μL blood | 194 (156-228) | 221 (111-279) P = .99† | 612 (444-708) P < .0001‡ | 379 (262-541) P = .023‡ |
| Hemoglobin, g/dL | 11.9 (11-15) | 11.3 (8.3-12.6) P = .021† | 13 (12.4-14.3) P = .012‡ | 14.8 (12.6-15.7) P = .003‡ |
| Hematocrit, % | 36.4 (32.9-43.6) | 32.3 (24.3-37.8) P < .0001† | 39.6 (38.1-41.8) P = .002‡ | 43.5 (39.1-46.3) P = .018‡ |
| RBC count, ×109/μL blood | 5.5 (4.9-5.8)§ | 4.0 (3.2-4.7) P = .0011† | 5.0 (4.7-5.4) P = .0002‡ | 5.5 (4.7-5.8) P = .0007‡ |
| Peripheral microscopic Plasmodium parasitemia, % (n/N) | 0 | 31 (5/16) | 0 | 33 (2/6) |
| Parameter . | Spleen-intact controls (n = 20) . | Patients undergoing splenectomy (n = 16) . | ||
|---|---|---|---|---|
| Day 0 . | Day 60 . | Day 360∗ . | ||
| Age, y | 28 (26-31) | 27 (17-35) | ||
| Males, % (n/N) | 40 (8/20) | 81 (13/16) | ||
| Papuan, % (n/N) | 95 (19/20) | 25 (4/16) | ||
| Splenectomy due to trauma, % (n/N) | — | 88 (14/16) | ||
| Platelet counts, ×103/μL blood | 194 (156-228) | 221 (111-279) P = .99† | 612 (444-708) P < .0001‡ | 379 (262-541) P = .023‡ |
| Hemoglobin, g/dL | 11.9 (11-15) | 11.3 (8.3-12.6) P = .021† | 13 (12.4-14.3) P = .012‡ | 14.8 (12.6-15.7) P = .003‡ |
| Hematocrit, % | 36.4 (32.9-43.6) | 32.3 (24.3-37.8) P < .0001† | 39.6 (38.1-41.8) P = .002‡ | 43.5 (39.1-46.3) P = .018‡ |
| RBC count, ×109/μL blood | 5.5 (4.9-5.8)§ | 4.0 (3.2-4.7) P = .0011† | 5.0 (4.7-5.4) P = .0002‡ | 5.5 (4.7-5.8) P = .0007‡ |
| Peripheral microscopic Plasmodium parasitemia, % (n/N) | 0 | 31 (5/16) | 0 | 33 (2/6) |
Median (interquartile range) shown, unless specified otherwise.
Splenectomized patients on day 360 restricted to n = 6.
Comparison spleen-intact controls vs day 0 patients (1-way analysis of variance).
Comparison day 0 vs day 60 or day 360 patients (1-way analysis of variance).
RBC counts missing for 16 spleen-intact individuals.