Results of the evaluation of TTCR24 and CR24 as surrogate markers for PFS at 8 years after randomization
| . | Estimations . | Value (95% CI) . |
|---|---|---|
| Parast et al17 | ||
| TTCR24 | Proportion explained by PFS24 | 0.75 (0.31-1.27) |
| Incremental value of TTCR24 | 0.20 (−0.23 to 0.86) | |
| Total surrogate property | 0.95 (0.27-1.87) | |
| Vandenberghe et al16 | ||
| CR24 | Natural indirect effect (risk) | 1.26 (1.11-1.42) |
| Natural direct effect (risk) | 1.03 (0.85-1.21) | |
| Mediated proportion | 0.90 (0.51-2.22) |
| . | Estimations . | Value (95% CI) . |
|---|---|---|
| Parast et al17 | ||
| TTCR24 | Proportion explained by PFS24 | 0.75 (0.31-1.27) |
| Incremental value of TTCR24 | 0.20 (−0.23 to 0.86) | |
| Total surrogate property | 0.95 (0.27-1.87) | |
| Vandenberghe et al16 | ||
| CR24 | Natural indirect effect (risk) | 1.26 (1.11-1.42) |
| Natural direct effect (risk) | 1.03 (0.85-1.21) | |
| Mediated proportion | 0.90 (0.51-2.22) |
Bold type indicates the main result of each analysis.