Table 2. Association between maternal... | American Society of Hematology

Table 2.

Association between maternal exposure to medical agents and child's neoplasms

Maternal exposure	Exposures, no. (%)	Patients, no. (/100 k)∗
Maternal exposure	Exposures, no. (%)	Leukemia (n = 29)	Brain tumor (n = 7)
Anticancer drugs	Yes 1 291 (1.4)	4† (309.8) ‡	0 (0.0)
Anticancer drugs	No 91 916 (98.6)	25 (27.2)	7 (7.6)
Ionizing radiation	Yes 2 145 (2.3)	2† (93.2)§	0 (0.0)
Ionizing radiation	No 91 062 (97.7)	27 (29.7)	7 (7.7)
Anesthetics	Yes 1 005 (1.1)	1 (99.5)‖	0 (0.0)
Anesthetics	No 92 202 (98.9)	28 (30.4)	7 (7.6)

Maternal exposure	Exposures, no. (%)	Patients, no. (/100 k)∗
Maternal exposure	Exposures, no. (%)	Leukemia (n = 29)	Brain tumor (n = 7)
Anticancer drugs	Yes 1 291 (1.4)	4† (309.8) ‡	0 (0.0)
Anticancer drugs	No 91 916 (98.6)	25 (27.2)	7 (7.6)
Ionizing radiation	Yes 2 145 (2.3)	2† (93.2)§	0 (0.0)
Ionizing radiation	No 91 062 (97.7)	27 (29.7)	7 (7.7)
Anesthetics	Yes 1 005 (1.1)	1 (99.5)‖	0 (0.0)
Anesthetics	No 92 202 (98.9)	28 (30.4)	7 (7.6)

/100 k, per 100 000 children.

One patient had a combined maternal exposure to anticancer and ionizing radiation.

P = .000012.

P = .0038.

P = .0032.