Table 1.

Correlation between percent GATA2+ bone marrow cells and clinicopathologic metrics in adult MDS cases

VariableP value, test used
Diagnosis < .001, J 
RS/SLD/MLD/U  
EB-1  
EB-2  
Age at diagnosis, y .863, S 
Sex .552, W 
Therapy related .317, W 
Marrow cellularity .960, S 
Marrow dysplasia   
Erythroid .509, W 
Myeloid .038, W 
Megakaryocyte .971, W 
Blood dysplasia  
Erythroid .857, W 
Myeloid .675, W 
Megakaryocyte .834, W 
Cytopenia  
RBCs Insufficient Data 
Neutrophils .576, W 
Platelets .119, W 
Ring sideroblasts  .270, J 
Blasts (%) < .001, S 
Abnormal cytogenetics .378, W 
Complex cytogenetics .048, W 
Number of P/LP mutations .579, J 
0-1  
2-3  
4-6  
VariableP value, test used
Diagnosis < .001, J 
RS/SLD/MLD/U  
EB-1  
EB-2  
Age at diagnosis, y .863, S 
Sex .552, W 
Therapy related .317, W 
Marrow cellularity .960, S 
Marrow dysplasia   
Erythroid .509, W 
Myeloid .038, W 
Megakaryocyte .971, W 
Blood dysplasia  
Erythroid .857, W 
Myeloid .675, W 
Megakaryocyte .834, W 
Cytopenia  
RBCs Insufficient Data 
Neutrophils .576, W 
Platelets .119, W 
Ring sideroblasts  .270, J 
Blasts (%) < .001, S 
Abnormal cytogenetics .378, W 
Complex cytogenetics .048, W 
Number of P/LP mutations .579, J 
0-1  
2-3  
4-6  

Significance indicated in bold. EB, excess blasts; MLD, multilineage dysplasia; P/LP, pathogenic/likely pathogenic; RBCs, red blood cells; RS, ring sideroblasts; SLD, single lineage dysplasia; U, unclassifiable.

Statistical tests: J, Jonckheere; W, Wilcoxon rank-sum; S, Spearman correlation; K, Kruskal-Walls.

n = 46.

n = 42.

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