Correlation between percent GATA2+ bone marrow cells and clinicopathologic metrics in adult MDS cases
Variable . | P value, test used . |
---|---|
Diagnosis | < .001, J |
RS/SLD/MLD/U | |
EB-1 | |
EB-2 | |
Age at diagnosis, y | .863, S |
Sex | .552, W |
Therapy related | .317, W |
Marrow cellularity | .960, S |
Marrow dysplasia∗ | |
Erythroid | .509, W |
Myeloid | .038, W |
Megakaryocyte | .971, W |
Blood dysplasia | |
Erythroid | .857, W |
Myeloid | .675, W |
Megakaryocyte | .834, W |
Cytopenia | |
RBCs | Insufficient Data |
Neutrophils | .576, W |
Platelets | .119, W |
Ring sideroblasts† | .270, J |
Blasts (%) | < .001, S |
Abnormal cytogenetics | .378, W |
Complex cytogenetics | .048, W |
Number of P/LP mutations | .579, J |
0-1 | |
2-3 | |
4-6 |
Variable . | P value, test used . |
---|---|
Diagnosis | < .001, J |
RS/SLD/MLD/U | |
EB-1 | |
EB-2 | |
Age at diagnosis, y | .863, S |
Sex | .552, W |
Therapy related | .317, W |
Marrow cellularity | .960, S |
Marrow dysplasia∗ | |
Erythroid | .509, W |
Myeloid | .038, W |
Megakaryocyte | .971, W |
Blood dysplasia | |
Erythroid | .857, W |
Myeloid | .675, W |
Megakaryocyte | .834, W |
Cytopenia | |
RBCs | Insufficient Data |
Neutrophils | .576, W |
Platelets | .119, W |
Ring sideroblasts† | .270, J |
Blasts (%) | < .001, S |
Abnormal cytogenetics | .378, W |
Complex cytogenetics | .048, W |
Number of P/LP mutations | .579, J |
0-1 | |
2-3 | |
4-6 |
Significance indicated in bold. EB, excess blasts; MLD, multilineage dysplasia; P/LP, pathogenic/likely pathogenic; RBCs, red blood cells; RS, ring sideroblasts; SLD, single lineage dysplasia; U, unclassifiable.
Statistical tests: J, Jonckheere; W, Wilcoxon rank-sum; S, Spearman correlation; K, Kruskal-Walls.
n = 46.
n = 42.